C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000586569 TNFRSF11A-001 ENSG00000141655 9606 + 18:62325315-62391292 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000586569
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000586569 0.091±0.00 1.094±0.00 0.355±0.00 0.712±0.51 0.085±0.00 0.180±0.00 0.070±0.05 0.094±0.05 0.028±0.00 0.194±0.13 0.624±0.20 0.254±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00071U CIL_00071U_0001 CGP 18:62187258-62391292
CIL_00076G CIL_00076G_0001 CGP 18:62325287-62587709

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0002250 IMP adaptive immune response
GO:0002548 NAS monocyte chemotaxis
GO:0004872 TAS receptor activity
GO:0004888 IDA transmembrane signaling receptor activity
GO:0005031 ISS tumor necrosis factor-activated receptor activity
GO:0005515 IPI:IEA protein binding
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0007275 IEA multicellular organismal development
GO:0008284 TAS positive regulation of cell proliferation
GO:0009314 IEA response to radiation
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0019955 IPI cytokine binding
GO:0030316 IMP osteoclast differentiation
GO:0032496 ISS response to lipopolysaccharide
GO:0033209 ISS tumor necrosis factor-mediated signaling pathway
GO:0034097 IMP response to cytokine
GO:0034612 ISS response to tumor necrosis factor
GO:0043507 IMP positive regulation of JUN kinase activity
GO:0046872 IEA metal ion binding
GO:0048535 IEA lymph node development
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0060086 ISS circadian temperature homeostasis
GO:0060749 IEA mammary gland alveolus development
GO:0070555 ISS response to interleukin-1
GO:0071812 ISS positive regulation of fever generation by positive regulation of prostaglandin secretion
GO:0071847 IMP TNFSF11-mediated signaling pathway
GO:0071848 IMP positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027559 Tnfrsf11a-001 protein_coding Mus_musculus 0 1105
ENSMUST00000187812 Tnfrsf11a-002 retained_intron Mus_musculus 0 433
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.0000000004 73

Loading