C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adenylosuccinate lyase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000623063 ADSL-001 ENSG00000239900 9606 + 22:40346500-40369367 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartMuscleENST00000623063
Transcript ID Heart Muscle
ENST00000623063 1.856±0.00 7.883±3.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006F2 CIL_0006F2_0001 CGP 22:40044817-40369367

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0003824 IEA catalytic activity
GO:0004018 IDA:IEA N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006163 IEA purine nucleotide metabolic process
GO:0006164 IC purine nucleotide biosynthetic process
GO:0006167 IDA AMP biosynthetic process
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0007584 IEA response to nutrient
GO:0008152 IDA metabolic process
GO:0009060 IEA aerobic respiration
GO:0009152 IEA purine ribonucleotide biosynthetic process
GO:0009156 IEA ribonucleoside monophosphate biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0014850 IEA response to muscle activity
GO:0042594 IEA response to starvation
GO:0044208 IEA 'de novo' AMP biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0051262 IDA protein tetramerization
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070626 IEA (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023043 Adsl-001 protein_coding Mus_musculus 0 1659
ENSMUST00000164806 Adsl-003 protein_coding Mus_musculus 0 1415
ENSMUST00000168756 Adsl-004 protein_coding Mus_musculus 0 1238
ENSMUST00000166711 Adsl-002 nonsense_mediated_decay Mus_musculus 0 667
ENSMUST00000164371 Adsl-005 retained_intron Mus_musculus 0 416
ENSMUST00000169238 Adsl-006 nonsense_mediated_decay Mus_musculus 0 416
ENSMUST00000170354 Adsl-007 protein_coding Mus_musculus 1e-27 130
ENSMUST00000148884 Blzf1-004 retained_intron Mus_musculus 0.0003 53

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