C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SLIT-ROBO Rho GTPase activating protein 2a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000032161 srgap2a 7955 - 11:22239998-22418377 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000045391 srgap2a-201 22239998-22416104 protein_coding
  ENSDART00000103865 srgap2a-001 22242498-22418377 protein_coding
  ENSDART00000138665 srgap2a-002 22413127-22418362 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverMuscleENSDART00000045391ENSDART00000103865
Transcript ID Brain Liver Muscle
ENSDART00000045391 7.379±5.82 0.094±0.00 1.052±0.00
ENSDART00000103865 N/A 0.067±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VZ CIL_0005VZ_0001 CGP 11:22197809-22418377
CIL_00012Y CIL_00012Y_0001 CGP 11:22239998-22431726

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005096 IEA GTPase activator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0007165 IEA signal transduction
GO:0007399 IEA nervous system development
GO:0014069 ISS postsynaptic density
GO:0016020 IEA membrane
GO:0030027 IEA lamellipodium
GO:0030054 IEA cell junction
GO:0030675 ISS Rac GTPase activator activity
GO:0031410 IEA cytoplasmic vesicle
GO:0032855 ISS positive regulation of Rac GTPase activity
GO:0042803 ISS protein homodimerization activity
GO:0042995 IEA cell projection
GO:0044327 ISS dendritic spine head
GO:0045202 IEA synapse
GO:0045211 ISS postsynaptic membrane
GO:0045335 ISS phagocytic vesicle
GO:0046847 ISS filopodium assembly
GO:0048365 ISS Rac GTPase binding
GO:0048812 ISS neuron projection morphogenesis
GO:0051014 ISS actin filament severing
GO:0060996 ISS dendritic spine development
GO:2001223 ISS negative regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000171943 SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C protein_coding Homo_sapiens
ENSG00000196369 SRGAP2B SLIT-ROBO Rho GTPase activating protein 2B protein_coding Homo_sapiens
ENSG00000266028 SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 protein_coding Homo_sapiens
ENSMUSG00000026425 Srgap2 SLIT-ROBO Rho GTPase activating protein 2 protein_coding Mus_musculus

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