C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SLIT-ROBO Rho GTPase activating protein 2a
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000045391 srgap2a-201 ENSDARG00000032161 7955 - 11:22239998-22416104 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverMuscleENSDART00000045391
Transcript ID Brain Liver Muscle
ENSDART00000045391 7.379±5.82 0.094±0.00 1.052±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VZ CIL_0005VZ_0001 CGP 11:22197809-22418377
CIL_00012Y CIL_00012Y_0001 CGP 11:22239998-22431726

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005096 IEA GTPase activator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0007165 IEA signal transduction
GO:0007399 IEA nervous system development
GO:0014069 ISS postsynaptic density
GO:0016020 IEA membrane
GO:0030027 IEA lamellipodium
GO:0030054 IEA cell junction
GO:0030675 ISS Rac GTPase activator activity
GO:0031410 IEA cytoplasmic vesicle
GO:0032855 ISS positive regulation of Rac GTPase activity
GO:0042803 ISS protein homodimerization activity
GO:0042995 IEA cell projection
GO:0044327 ISS dendritic spine head
GO:0045202 IEA synapse
GO:0045211 ISS postsynaptic membrane
GO:0045335 ISS phagocytic vesicle
GO:0046847 ISS filopodium assembly
GO:0048365 ISS Rac GTPase binding
GO:0048812 ISS neuron projection morphogenesis
GO:0051014 ISS actin filament severing
GO:0060996 ISS dendritic spine development
GO:2001223 ISS negative regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000097588 Srgap2-001 protein_coding Mus_musculus 0 1253
ENSMUST00000185445 Srgap2-009 protein_coding Mus_musculus 0 233
ENSMUST00000185596 Srgap2-005 protein_coding Mus_musculus 0 987
ENSMUST00000186543 Srgap2-004 protein_coding Mus_musculus 0 1253
ENSMUST00000187273 Srgap2-010 protein_coding Mus_musculus 3e-34 148
ENSMUST00000189893 Srgap2-002 retained_intron Mus_musculus 0 303
ENST00000304465 SRGAP2C-201 protein_coding Homo_sapiens 0 627
ENST00000367123 SRGAP2C-001 protein_coding Homo_sapiens 0 909
ENST00000419187 SRGAP2-201 protein_coding Homo_sapiens 0 649
ENST00000572793 SRGAP2-011 protein_coding Homo_sapiens 0 209
ENST00000573034 SRGAP2-001 protein_coding Homo_sapiens 0 1447
ENST00000579225 SRGAP2-007 protein_coding Homo_sapiens 0 215
ENST00000605242 SRGAP2-010 processed_transcript Homo_sapiens 0 300
ENST00000605551 SRGAP2D-001 unprocessed_pseudogene Homo_sapiens 0 643
ENST00000605610 SRGAP2-002 protein_coding Homo_sapiens 0 1461
ENST00000612199 SRGAP2B-001 protein_coding Homo_sapiens 0 946
ENST00000619678 SRGAP2B-201 protein_coding Homo_sapiens 0 649
ENST00000621582 SRGAP2B-005 nonsense_mediated_decay Homo_sapiens 0 243
ENST00000624873 SRGAP2-016 protein_coding Homo_sapiens 0 1461

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