C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: latent transforming growth factor beta binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000049323 LTBP1 9606 + 2:32946972-33399509 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000402934 LTBP1-008 33134625-33399357 protein_coding
  ENST00000404525 LTBP1-001 33134639-33399509 protein_coding
  ENST00000404816 LTBP1-014 32946972-33399359 protein_coding
  ENST00000407925 LTBP1-007 33134657-33399363 protein_coding
  ENST00000413303 LTBP1-006 33243662-33273711 protein_coding
  ENST00000415140 LTBP1-017 33275909-33347409 protein_coding
  ENST00000418533 LTBP1-201 33134597-33399506 protein_coding
  ENST00000422669 LTBP1-010 33301530-33363421 protein_coding
  ENST00000432635 LTBP1-016 33134406-33188676 protein_coding
  ENST00000468091 LTBP1-018 33252727-33273746 protein_coding
  ENST00000489740 LTBP1-003 33301632-33317940 processed_transcript
  ENST00000498013 LTBP1-011 33291484-33309482 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000402934ENST00000404525ENST00000404816ENST00000407925ENST00000418533ENST00000422669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000402934 5.795±0.00 2.694±0.00 N/A 2.476±0.00 2.194±0.00 7.285±0.00 4.018±0.00 6.057±0.00 N/A 12.839±0.00 1.707±0.00 4.654±0.00 N/A 12.071±11.12
ENST00000404525 N/A N/A 1.837±0.00 0.544±0.00 6.358±0.00 0.592±0.00 3.044±0.78 N/A 5.424±0.00 1.363±0.00 N/A 6.407±5.97 23.280±6.89 N/A
ENST00000404816 5.892±0.00 1.545±0.00 1.562±0.00 N/A 2.124±0.00 2.380±1.45 4.352±0.87 2.166±1.44 2.366±1.15 2.105±0.55 1.176±0.00 2.270±0.00 16.099±8.94 4.463±2.64
ENST00000407925 N/A 3.864±0.00 0.804±0.00 0.741±0.06 6.256±0.00 2.407±0.71 N/A N/A 7.388±0.00 4.446±0.51 2.131±0.00 3.776±0.81 N/A 9.850±5.78
ENST00000418533 N/A N/A N/A N/A 2.540±0.00 1.321±0.00 1.715±0.00 0.955±0.00 2.059±0.00 1.170±0.00 0.948±0.00 2.087±0.00 N/A N/A
ENST00000422669 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.787±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TE CIL_0003TE_0002 CGP 2:32628032-33399509
CIL_0000MZ CIL_0000MZ_0001 CGP 2:32946972-33564750

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005024 NAS transforming growth factor beta-activated receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005578 NAS proteinaceous extracellular matrix
GO:0007178 NAS transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0030198 TAS extracellular matrix organization
GO:0031012 IDA extracellular matrix
GO:0035583 TAS sequestering of TGFbeta in extracellular matrix
GO:0050431 IPI transforming growth factor beta binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056922 ltbp1 latent transforming growth factor beta binding protein 1 protein_coding Danio_rerio
ENSMUSG00000001870 Ltbp1 latent transforming growth factor beta binding protein 1 protein_coding Mus_musculus

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