C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glypican 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000063660 GPC1 9606 + 2:240435671-240468078 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264039 GPC1-001 240435671-240468078 protein_coding
  ENST00000420138 GPC1-002 240452811-240466330 protein_coding
  ENST00000425056 GPC1-009 240457965-240464939 protein_coding
  ENST00000426280 GPC1-007 240454838-240462484 protein_coding
  ENST00000427506 GPC1-008 240457434-240462568 protein_coding
  ENST00000455111 GPC1-010 240463397-240466200 protein_coding
  ENST00000466624 GPC1-011 240465527-240466793 processed_transcript
  ENST00000469694 GPC1-004 240442327-240466358 retained_intron
  ENST00000495100 GPC1-003 240458187-240466358 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264039ENST00000420138ENST00000425056ENST00000455111ENST00000466624ENST00000495100
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264039 18.305±0.00 9.621±0.00 0.450±0.00 16.671±15.04 18.404±16.86 7.866±6.89 29.166±27.46 15.961±12.29 12.329±10.63 5.487±5.12 23.649±17.80 37.357±32.16 31.902±4.64 27.273±13.32
ENST00000420138 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.774±0.00 8.851±0.00
ENST00000425056 N/A N/A 2.017±0.00 N/A 1.994±0.00 1.038±0.00 N/A N/A N/A 1.064±0.00 N/A N/A N/A N/A
ENST00000455111 N/A N/A N/A N/A N/A N/A N/A N/A 1.277±0.00 N/A N/A N/A N/A N/A
ENST00000466624 N/A N/A 0.752±0.00 5.091±0.00 1.453±0.00 N/A N/A N/A 2.858±0.00 1.257±0.00 N/A 34.039±0.00 53.038±0.00 23.840±0.00
ENST00000495100 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.169±0.00 N/A 0.780±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TM CIL_0007TM_0001 VISTA 2:239957940-240560738
CIL_0009AE CIL_0009AE_0001 VISTA 2:240068562-240673577
CIL_0003NP CIL_0003NP_0001 CGP 2:240139026-240468078
CIL_0004UD CIL_0004UD_0002 CGP 2:240435671-240569209

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0005507 IDA copper ion binding
GO:0005578 ISS:IEA proteinaceous extracellular matrix
GO:0005615 TAS extracellular space
GO:0005768 IEA endosome
GO:0005796 TAS Golgi lumen
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0006024 TAS glycosaminoglycan biosynthetic process
GO:0006027 TAS glycosaminoglycan catabolic process
GO:0007411 TAS axon guidance
GO:0007603 TAS phototransduction, visible light
GO:0014037 ISS Schwann cell differentiation
GO:0016020 IEA membrane
GO:0017134 ISS fibroblast growth factor binding
GO:0030200 IDA heparan sulfate proteoglycan catabolic process
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030204 TAS chondroitin sulfate metabolic process
GO:0031225 IEA anchored component of membrane
GO:0032288 ISS myelin assembly
GO:0040037 ISS negative regulation of fibroblast growth factor receptor signaling pathway
GO:0043202 TAS lysosomal lumen
GO:0043236 ISS laminin binding
GO:0043395 IEA heparan sulfate proteoglycan binding
GO:0044281 TAS small molecule metabolic process
GO:0045121 ISS membrane raft
GO:0070062 IDA extracellular vesicular exosome
GO:2001016 ISS positive regulation of skeletal muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019341 gpc1a glypican 1a protein_coding Danio_rerio
ENSDARG00000090456 GPC1 (2 of 3) glypican 1 protein_coding Danio_rerio
ENSDARG00000090585 gpc1b glypican 1b protein_coding Danio_rerio
ENSMUSG00000034220 Gpc1 glypican 1 protein_coding Mus_musculus

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