C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tumor protein p53 binding protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000382044 TP53BP1-001 ENSG00000067369 9606 - 15:43403061-43493171 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000382044
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000382044 2.370±0.00 1.014±0.00 1.376±0.00 4.060±0.64 1.412±0.07 2.019±0.14 3.258±0.00 5.152±0.00 1.875±1.35 2.266±0.16 2.526±0.00 5.831±2.71 1.543±0.69 7.996±1.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005YH CIL_0005YH_0001 CGP 15:43358172-43409771
CIL_0005YA CIL_0005YA_0001 CGP 15:43369221-43510728
CIL_0005YB CIL_0005YB_0001 CGP 15:43403061-43531620

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000724 TAS double-strand break repair via homologous recombination
GO:0000776 IEA kinetochore
GO:0000781 IDA chromosome, telomeric region
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001104 IMP RNA polymerase II transcription cofactor activity
GO:0002039 IPI p53 binding
GO:0003684 IEA damaged DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005657 IEA replication fork
GO:0005737 IDA cytoplasm
GO:0006281 TAS DNA repair
GO:0006302 TAS double-strand break repair
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0035064 IDA methylated histone binding
GO:0042162 IEA telomeric DNA binding
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0051091 IC positive regulation of sequence-specific DNA binding transcription factor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110648 Trp53bp1-001 protein_coding Mus_musculus 0 3570
ENSMUST00000147540 Trp53bp1-007 nonsense_mediated_decay Mus_musculus 0 3404
ENSMUST00000110647 Trp53bp1-002 protein_coding Mus_musculus 0 2815
ENSMUST00000135890 Trp53bp1-006 processed_transcript Mus_musculus 0 2615
ENSMUST00000131245 Trp53bp1-003 protein_coding Mus_musculus 0 2167
ENSMUST00000147554 Trp53bp1-016 processed_transcript Mus_musculus 0 953
ENSMUST00000132812 Trp53bp1-015 processed_transcript Mus_musculus 0 741
ENSMUST00000110658 Tubgcp4-002 protein_coding Mus_musculus 0 736
ENSMUST00000039541 Tubgcp4-001 protein_coding Mus_musculus 0 736
ENSMUST00000136617 Trp53bp1-004 processed_transcript Mus_musculus 0 665
ENSMUST00000186659 Tubgcp4-201 protein_coding Mus_musculus 0 654
ENSMUST00000144076 Tubgcp4-004 retained_intron Mus_musculus 0 654
ENSMUST00000138601 Tubgcp4-003 retained_intron Mus_musculus 0 654
ENSMUST00000124554 Trp53bp1-019 nonsense_mediated_decay Mus_musculus 0 638
ENSMUST00000154426 Trp53bp1-018 nonsense_mediated_decay Mus_musculus 0 614
ENSMUST00000140285 Trp53bp1-005 retained_intron Mus_musculus 0 508
ENSMUST00000129752 Trp53bp1-010 nonsense_mediated_decay Mus_musculus 0 488
ENSMUST00000124060 Trp53bp1-008 retained_intron Mus_musculus 0 370
ENSMUST00000142400 Trp53bp1-017 protein_coding Mus_musculus 0 263
ENSMUST00000143305 Tubgcp4-007 retained_intron Mus_musculus 0 211
ENSMUST00000154318 Tubgcp4-014 retained_intron Mus_musculus 0 196
ENSMUST00000131426 Trp53bp1-009 retained_intron Mus_musculus 3.00018e-42 180
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.0000003 64
ENSMUST00000024742 Nfkbie-201 protein_coding Mus_musculus 0.000001 62

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