C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM and senescent cell antigen-like domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072163 LIMS2 9606 - 2:127638381-127681786 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324938 LIMS2-005 127638426-127664546 protein_coding
  ENST00000355119 LIMS2-001 127638428-127675190 protein_coding
  ENST00000409254 LIMS2-012 127639197-127650538 protein_coding
  ENST00000409286 LIMS2-009 127638426-127643228 protein_coding
  ENST00000409455 LIMS2-004 127638428-127674309 protein_coding
  ENST00000409754 LIMS2-008 127638426-127644110 protein_coding
  ENST00000409808 LIMS2-002 127638428-127675286 protein_coding
  ENST00000410011 LIMS2-003 127638428-127681786 protein_coding
  ENST00000410038 LIMS2-006 127638470-127648253 protein_coding
  ENST00000413578 LIMS2-013 127638983-127650538 nonsense_mediated_decay
  ENST00000426981 LIMS2-007 127638381-127642131 protein_coding
  ENST00000466410 LIMS2-011 127638428-127664452 retained_intron
  ENST00000469300 LIMS2-014 127638425-127656085 retained_intron
  ENST00000476932 LIMS2-017 127638426-127664419 retained_intron
  ENST00000484252 LIMS2-015 127638428-127642351 retained_intron
  ENST00000494613 LIMS2-016 127638426-127640403 processed_transcript
  ENST00000545738 LIMS2-018 127638721-127675102 protein_coding
  ENST00000582671 LIMS2-020 127642125-127646678 processed_transcript
  ENST00000612860 LIMS2-201 127638430-127644112 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324938ENST00000355119ENST00000409254ENST00000409286ENST00000409455ENST00000409754ENST00000413578ENST00000469300ENST00000494613ENST00000545738ENST00000612860
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324938 N/A N/A N/A N/A N/A N/A N/A N/A 3.321±0.00 N/A 0.627±0.00 3.196±0.00 13.558±0.00 2.266±0.00
ENST00000355119 18.494±0.00 35.867±0.00 0.833±0.00 3.586±0.00 19.506±17.90 244.297±0.00 70.447±0.00 17.507±0.00 3.633±0.38 18.095±15.98 6.794±0.00 17.810±1.41 27.726±1.98 39.350±0.00
ENST00000409254 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.665±0.00 7.526±0.00 3.854±0.00
ENST00000409286 N/A N/A N/A N/A N/A N/A N/A 6.211±0.00 2.566±0.00 N/A N/A N/A N/A N/A
ENST00000409455 N/A N/A N/A N/A N/A N/A 0.910±0.00 N/A N/A 0.906±0.00 N/A N/A N/A N/A
ENST00000409754 N/A N/A N/A N/A N/A N/A N/A 0.591±0.00 N/A N/A N/A N/A N/A N/A
ENST00000413578 15.022±0.00 N/A N/A 5.513±0.00 N/A N/A N/A 3.585±0.00 N/A N/A N/A N/A N/A 17.165±0.00
ENST00000469300 N/A N/A N/A N/A N/A N/A N/A N/A 1.211±0.00 N/A N/A 0.059±0.00 N/A N/A
ENST00000494613 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.728±0.00 N/A N/A
ENST00000545738 N/A 16.001±0.00 0.895±0.00 N/A N/A N/A N/A 1.586±0.00 N/A N/A N/A 9.138±0.00 N/A N/A
ENST00000612860 N/A 17.534±0.00 N/A N/A 21.779±0.00 N/A N/A N/A N/A N/A 1.831±0.00 18.079±0.00 15.478±1.07 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000197 CIL_000197_0001 CGP 2:127638381-127681786

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0008270 IEA zinc ion binding
GO:0016337 IEA single organismal cell-cell adhesion
GO:0034329 TAS cell junction assembly
GO:0043066 IEA negative regulation of apoptotic process
GO:0045216 IEA cell-cell junction organization
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:2000178 IEA negative regulation of neural precursor cell proliferation
GO:2000346 IEA negative regulation of hepatocyte proliferation
GO:2001046 IEA positive regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014976 lims2 LIM and senescent cell antigen-like domains 2 protein_coding Danio_rerio
ENSDARG00000026985 lims1 LIM and senescent cell antigen-like domains 1 protein_coding Danio_rerio
ENSMUSG00000024395 Lims2 LIM and senescent cell antigen like domains 2 protein_coding Mus_musculus

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