C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 8 (sodium/calcium exchanger), member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100678 SLC8A3 9606 - 14:70044217-70189070 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216568 SLC8A3-006 70044255-70080206 protein_coding
  ENST00000356921 SLC8A3-001 70044217-70189070 protein_coding
  ENST00000357887 SLC8A3-201 70044220-70189070 protein_coding
  ENST00000381269 SLC8A3-003 70044217-70189070 protein_coding
  ENST00000394330 SLC8A3-007 70044419-70080180 protein_coding
  ENST00000494208 SLC8A3-002 70044217-70189070 nonsense_mediated_decay
  ENST00000528359 SLC8A3-005 70045947-70168484 protein_coding
  ENST00000533541 SLC8A3-008 70046075-70080180 protein_coding
  ENST00000533899 SLC8A3-009 70059106-70060939 processed_transcript
  ENST00000534137 SLC8A3-004 70045947-70168484 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216568ENST00000356921ENST00000381269ENST00000394330ENST00000494208ENST00000533541ENST00000534137
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216568 N/A 0.118±0.00 0.941±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.043±0.00 N/A
ENST00000356921 N/A N/A 1.677±0.78 0.092±0.00 N/A N/A N/A 0.419±0.00 N/A 1.105±0.00 N/A N/A 0.110±0.00
ENST00000381269 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.436±0.00 0.013±0.00 N/A 0.071±0.03
ENST00000394330 N/A N/A 0.651±0.00 N/A N/A 0.047±0.00 N/A 0.010±0.00 0.184±0.07 N/A 0.027±0.00 N/A N/A
ENST00000494208 0.077±0.00 N/A 0.798±0.00 N/A 0.025±0.01 0.020±0.00 0.006±0.00 N/A 0.253±0.00 1.695±1.13 0.013±0.00 0.022±0.01 N/A
ENST00000533541 N/A N/A N/A 0.060±0.00 N/A 0.022±0.00 N/A 0.010±0.00 N/A N/A N/A 0.019±0.01 0.017±0.00
ENST00000534137 N/A N/A N/A N/A 0.016±0.00 N/A N/A N/A 0.154±0.00 N/A 0.016±0.00 N/A 0.123±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002M6 CIL_0002M6_0001 CGP 14:69854131-70189070
CIL_0006J1 CIL_0006J1_0002 CGP 14:70044217-70359731

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0005432 IEA calcium:sodium antiporter activity
GO:0005516 IEA calmodulin binding
GO:0005739 IEA mitochondrion
GO:0005874 IEA microtubule
GO:0005886 TAS plasma membrane
GO:0006811 TAS ion transport
GO:0006814 IEA sodium ion transport
GO:0006816 IEA calcium ion transport
GO:0007154 IEA cell communication
GO:0007596 TAS blood coagulation
GO:0015368 IEA calcium:cation antiporter activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0021537 IEA telencephalon development
GO:0030001 IEA metal ion transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0042383 IEA sarcolemma
GO:0042995 IEA cell projection
GO:0043025 IEA neuronal cell body
GO:0043197 IEA dendritic spine
GO:0055085 TAS:IEA transmembrane transport
GO:0060402 IEA calcium ion transport into cytosol
GO:0070588 IEA calcium ion transmembrane transport
GO:0071320 IEA cellular response to cAMP
GO:1990034 IEA calcium ion export from cell
GO:1990035 IEA calcium ion import into cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004931 slc8a3 solute carrier family 8 (sodium-calcium exchanger), member 3 protein_coding Danio_rerio
ENSMUSG00000079055 Slc8a3 solute carrier family 8 (sodium/calcium exchanger), member 3 protein_coding Mus_musculus

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