C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vacuolar protein sorting 4 homolog B (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119541 VPS4B 9606 - 18:63389190-63422483 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000238497 VPS4B-001 63389190-63422463 protein_coding
  ENST00000588059 VPS4B-004 63393444-63422463 nonsense_mediated_decay
  ENST00000588323 VPS4B-008 63390863-63397124 processed_transcript
  ENST00000589604 VPS4B-005 63396590-63422463 retained_intron
  ENST00000591383 VPS4B-007 63399255-63404714 processed_transcript
  ENST00000591475 VPS4B-006 63396342-63422483 retained_intron
  ENST00000591519 VPS4B-003 63407376-63422390 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000238497ENST00000588059ENST00000589604ENST00000591383ENST00000591475ENST00000591519
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000238497 11.535±0.00 9.086±0.00 1.307±0.00 7.002±3.27 8.385±3.49 4.429±1.37 2.226±1.72 8.911±3.33 3.793±0.00 5.001±0.01 0.585±0.07 6.681±2.61 11.752±2.32 8.450±2.18
ENST00000588059 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.285±0.00 N/A N/A N/A
ENST00000589604 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.312±0.00
ENST00000591383 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.471±0.00 20.865±0.00 16.929±0.00
ENST00000591475 N/A N/A 1.256±0.00 N/A N/A N/A 0.618±0.00 N/A N/A 1.460±0.00 0.189±0.00 N/A N/A N/A
ENST00000591519 N/A N/A 3.105±0.00 N/A 7.992±0.00 N/A N/A N/A N/A 5.814±0.00 1.460±0.00 7.491±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000B7 CIL_0000B7_0002 CGP 18:63327726-63422483
CIL_00076J CIL_00076J_0001 CGP 18:63389190-63505085

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IMP:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005764 IDA lysosome
GO:0005768 IDA endosome
GO:0005769 IDA early endosome
GO:0005770 IDA late endosome
GO:0005774 IDA vacuolar membrane
GO:0005829 IDA cytosol
GO:0006200 IMP ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006813 IEA potassium ion transport
GO:0007032 IEA endosome organization
GO:0007049 IEA cell cycle
GO:0008022 IPI protein C-terminus binding
GO:0009378 IEA four-way junction helicase activity
GO:0010008 IDA endosome membrane
GO:0015031 IEA protein transport
GO:0016032 TAS viral process
GO:0016197 IMP endosomal transport
GO:0016887 IMP:IEA ATPase activity
GO:0019058 TAS viral life cycle
GO:0030301 IEA cholesterol transport
GO:0032367 IMP intracellular cholesterol transport
GO:0032510 IMP endosome to lysosome transport via multivesicular body sorting pathway
GO:0033993 IDA response to lipid
GO:0042623 NAS ATPase activity, coupled
GO:0050792 IMP regulation of viral process
GO:0051301 IEA cell division
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:1902188 IMP positive regulation of viral release from host cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069175 vps4b vacuolar protein sorting 4b (yeast) protein_coding Danio_rerio
ENSMUSG00000009907 Vps4b vacuolar protein sorting 4b (yeast) protein_coding Mus_musculus

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