C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitochondrial tRNA translation optimization 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135297 MTO1 9606 + 6:73461578-73509236 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370300 MTO1-003 73461765-73501452 protein_coding
  ENST00000370305 MTO1-007 73461746-73500923 protein_coding
  ENST00000370308 MTO1-002 73461765-73501096 retained_intron
  ENST00000415228 MTO1-005 73461765-73501096 nonsense_mediated_decay
  ENST00000415954 MTO1-012 73461578-73501096 protein_coding
  ENST00000442897 MTO1-014 73461742-73479972 nonsense_mediated_decay
  ENST00000445187 MTO1-006 73480000-73482534 nonsense_mediated_decay
  ENST00000462039 MTO1-004 73461795-73501050 retained_intron
  ENST00000466977 MTO1-009 73473553-73480171 retained_intron
  ENST00000485082 MTO1-008 73466263-73471795 retained_intron
  ENST00000487960 MTO1-010 73480166-73481028 retained_intron
  ENST00000498286 MTO1-001 73461578-73509236 protein_coding
  ENST00000518210 MTO1-016 73462143-73473411 processed_transcript
  ENST00000520366 MTO1-013 73480063-73480762 processed_transcript
  ENST00000521032 MTO1-015 73461747-73473474 nonsense_mediated_decay
  ENST00000521156 MTO1-019 73482115-73501038 protein_coding
  ENST00000522205 MTO1-011 73461778-73473532 nonsense_mediated_decay
  ENST00000523763 MTO1-017 73482132-73500701 nonsense_mediated_decay
  ENST00000524046 MTO1-018 73480296-73492325 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370300ENST00000370305ENST00000370308ENST00000415228ENST00000415954ENST00000445187ENST00000462039ENST00000498286ENST00000521156ENST00000522205
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370300 1.049±0.00 1.783±0.00 N/A N/A 1.234±0.00 N/A 0.997±0.00 N/A 1.652±0.00 N/A N/A 1.986±0.00 0.984±0.05 N/A
ENST00000370305 2.198±0.00 2.685±0.00 N/A 2.972±0.00 1.785±0.00 3.287±0.00 2.118±0.00 3.890±0.00 2.174±0.00 2.184±0.55 2.103±1.16 2.013±0.47 0.861±0.00 10.518±0.00
ENST00000370308 N/A N/A N/A 4.255±0.00 1.010±0.00 4.331±0.00 1.323±0.00 4.829±0.00 3.017±0.00 N/A 1.033±0.00 6.997±0.00 1.625±0.33 12.013±0.00
ENST00000415228 N/A 2.093±0.00 N/A N/A 1.196±0.24 1.207±0.00 1.319±0.00 3.221±0.00 1.726±0.00 1.398±0.00 N/A 2.476±0.23 1.327±0.02 7.586±0.00
ENST00000415954 0.971±0.00 N/A 2.711±0.00 1.735±0.05 1.146±0.00 N/A 0.507±0.00 1.702±0.06 N/A 1.604±0.00 0.581±0.00 1.820±0.00 N/A N/A
ENST00000445187 N/A N/A 3.297±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 8.708±0.00 N/A N/A
ENST00000462039 N/A N/A 0.645±0.00 N/A N/A N/A 0.588±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000498286 N/A N/A N/A 0.452±0.00 N/A 0.240±0.00 0.257±0.00 0.421±0.12 0.282±0.01 0.323±0.00 0.167±0.00 0.276±0.00 N/A N/A
ENST00000521156 N/A N/A N/A N/A N/A 2.182±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000522205 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.704±0.00 21.758±0.00 7.436±0.00 40.353±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PO CIL_0006PO_0001 CGP 6:73461578-73523797

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002098 IEA tRNA wobble uridine modification
GO:0005739 IEA mitochondrion
GO:0008033 IEA tRNA processing
GO:0016491 IEA oxidoreductase activity
GO:0044822 IDA poly(A) RNA binding
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process
GO:0070899 IEA mitochondrial tRNA wobble uridine modification

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055679 mto1 mitochondrial translation optimization 1 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000032342 Mto1 mitochondrial translation optimization 1 homolog (S. cerevisiae) protein_coding Mus_musculus

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