C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: syndecan binding protein (syntenin)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137575 SDCBP 9606 + 8:58552924-58582860 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260130 SDCBP-001 58553169-58582860 protein_coding
  ENST00000413219 SDCBP-002 58553217-58582830 protein_coding
  ENST00000424270 SDCBP-004 58553237-58582056 protein_coding
  ENST00000447182 SDCBP-003 58553216-58582846 protein_coding
  ENST00000447267 SDCBP-012 58565016-58581759 protein_coding
  ENST00000519115 SDCBP-013 58553261-58578384 retained_intron
  ENST00000520168 SDCBP-006 58553255-58582053 protein_coding
  ENST00000520228 SDCBP-009 58570712-58578070 retained_intron
  ENST00000522243 SDCBP-008 58552924-58572301 processed_transcript
  ENST00000522843 SDCBP-010 58553262-58576366 retained_intron
  ENST00000523441 SDCBP-011 58577993-58579949 retained_intron
  ENST00000523483 SDCBP-005 58553254-58582858 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260130ENST00000413219ENST00000424270ENST00000447182ENST00000447267ENST00000519115ENST00000520228ENST00000522843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260130 47.072±0.00 27.546±0.00 N/A 14.568±0.00 33.881±0.00 32.431±0.00 7.171±0.00 8.824±0.00 3.702±0.00 49.309±0.00 4.005±0.00 15.567±8.50 14.264±2.39 20.945±0.00
ENST00000413219 N/A 9.179±0.00 N/A N/A 5.648±0.00 N/A 12.665±0.00 12.824±9.96 6.273±0.00 17.511±8.98 5.445±0.00 28.228±0.00 55.519±2.44 7.017±0.00
ENST00000424270 52.704±0.00 14.841±0.00 2.508±0.00 17.339±0.00 19.882±0.00 15.747±7.91 5.984±0.00 4.834±0.00 N/A N/A 4.184±1.62 20.060±9.10 88.209±0.00 9.639±0.00
ENST00000447182 42.804±0.00 20.402±0.00 3.280±0.00 13.177±6.61 18.682±6.62 24.298±18.04 13.278±9.20 12.298±8.80 7.130±1.28 38.902±19.32 4.504±1.20 14.465±5.15 35.755±6.79 13.591±4.84
ENST00000447267 N/A N/A N/A N/A N/A N/A N/A 4.799±0.00 N/A N/A N/A N/A N/A 6.283±0.00
ENST00000519115 N/A N/A N/A 7.408±0.00 9.582±0.00 N/A N/A 8.882±0.00 N/A 25.903±0.00 N/A N/A N/A N/A
ENST00000520228 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.566±0.00
ENST00000522843 N/A N/A 3.915±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CM CIL_0008CM_0001 VISTA 8:57955651-58557562
CIL_0001T7 CIL_0001T7_0001 CGP 8:58490178-58582860
CIL_0002RG CIL_0002RG_0001 CGP 8:58552924-58659844

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001948 IEA glycoprotein binding
GO:0005109 IPI frizzled binding
GO:0005137 ISS interleukin-5 receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005634 NAS nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0005856 NAS cytoskeleton
GO:0005886 IDA plasma membrane
GO:0005895 ISS interleukin-5 receptor complex
GO:0005912 NAS adherens junction
GO:0006612 NAS protein targeting to membrane
GO:0006930 NAS substrate-dependent cell migration, cell extension
GO:0007265 IEA Ras protein signal transduction
GO:0007268 NAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008022 IEA protein C-terminus binding
GO:0008093 NAS cytoskeletal adaptor activity
GO:0016020 NAS membrane
GO:0019838 IEA growth factor binding
GO:0030036 NAS actin cytoskeleton organization
GO:0031982 IDA vesicle
GO:0035556 NAS intracellular signal transduction
GO:0042043 IEA neurexin family protein binding
GO:0042327 IDA positive regulation of phosphorylation
GO:0042802 IPI identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0045545 IPI syndecan binding
GO:0046330 IC positive regulation of JNK cascade
GO:0046875 IEA ephrin receptor binding
GO:0046982 IPI protein heterodimerization activity
GO:0047485 IPI protein N-terminus binding
GO:0050839 IEA cell adhesion molecule binding
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030097 sdcbp syndecan binding protein (syntenin) protein_coding Danio_rerio
ENSMUSG00000028249 Sdcbp syndecan binding protein protein_coding Mus_musculus

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