C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histidine decarboxylase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140287 HDC 9606 - 15:50241947-50266026 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267845 HDC-001 50241947-50266026 protein_coding
  ENST00000543581 HDC-004 50242013-50265666 protein_coding
  ENST00000558679 HDC-003 50253726-50265965 retained_intron
  ENST00000558761 HDC-002 50252920-50265726 retained_intron
  ENST00000559190 HDC-008 50253124-50263315 retained_intron
  ENST00000559683 HDC-007 50254552-50263429 protein_coding
  ENST00000559816 HDC-005 50241947-50253305 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000267845ENST00000543581ENST00000558679ENST00000558761ENST00000559190ENST00000559683ENST00000559816
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000267845 N/A N/A N/A 0.049±0.00 0.259±0.00 N/A N/A N/A 0.116±0.00 N/A N/A N/A N/A N/A
ENST00000543581 N/A N/A N/A 0.045±0.00 N/A N/A 0.135±0.00 0.207±0.00 N/A 3.235±0.00 N/A 0.063±0.00 0.124±0.00 0.382±0.05
ENST00000558679 N/A N/A N/A 0.119±0.00 0.057±0.00 0.240±0.00 N/A 0.136±0.00 0.253±0.00 N/A N/A N/A N/A N/A
ENST00000558761 0.048±0.00 N/A N/A N/A 0.329±0.00 N/A N/A N/A N/A 0.706±0.00 N/A N/A 0.070±0.00 N/A
ENST00000559190 N/A 1.137±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.192±0.16 N/A 0.372±0.00
ENST00000559683 0.254±0.00 N/A N/A N/A N/A 1.324±0.00 N/A N/A 0.352±0.00 N/A N/A N/A 0.245±0.00 N/A
ENST00000559816 0.146±0.00 1.600±0.00 0.129±0.00 N/A 0.233±0.05 N/A 0.026±0.01 0.032±0.00 0.231±0.00 4.635±0.00 0.280±0.00 0.678±0.00 0.056±0.04 0.514±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002E7 CIL_0002E7_0001 CGP 15:50182196-50266026
CIL_0002E6 CIL_0002E6_0001 CGP 15:50241947-50355408

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001694 IEA histamine biosynthetic process
GO:0004398 IDA histidine decarboxylase activity
GO:0005829 TAS cytosol
GO:0006520 IEA cellular amino acid metabolic process
GO:0006547 TAS histidine metabolic process
GO:0006548 IDA histidine catabolic process
GO:0016831 IEA carboxy-lyase activity
GO:0019752 IEA carboxylic acid metabolic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042423 IEA catecholamine biosynthetic process
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075454 hdc histidine decarboxylase protein_coding Danio_rerio
ENSMUSG00000027360 Hdc histidine decarboxylase protein_coding Mus_musculus

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