C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, F
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142949 PTPRF 9606 + 1:43525187-43623666 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000359947 PTPRF-001 43530876-43623666 protein_coding
  ENST00000372405 PTPRF-004 43538198-43580078 processed_transcript
  ENST00000372407 PTPRF-005 43598839-43623663 protein_coding
  ENST00000412568 PTPRF-014 43591021-43622283 protein_coding
  ENST00000414879 PTPRF-006 43591450-43622842 protein_coding
  ENST00000429895 PTPRF-015 43591053-43623654 protein_coding
  ENST00000436724 PTPRF-003 43530903-43580078 processed_transcript
  ENST00000437607 PTPRF-013 43545076-43579284 protein_coding
  ENST00000438120 PTPRF-002 43530890-43622357 protein_coding
  ENST00000463041 PTPRF-012 43605582-43606868 processed_transcript
  ENST00000467464 PTPRF-011 43582480-43591118 processed_transcript
  ENST00000477970 PTPRF-007 43613140-43622863 processed_transcript
  ENST00000481019 PTPRF-010 43528562-43553539 processed_transcript
  ENST00000496043 PTPRF-009 43525187-43553519 processed_transcript
  ENST00000496447 PTPRF-008 43598074-43623666 processed_transcript
  ENST00000617451 PTPRF-201 43530876-43579285 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000359947ENST00000372407ENST00000414879ENST00000429895ENST00000437607ENST00000438120ENST00000477970ENST00000496447ENST00000617451
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000359947 N/A 1.267±0.00 N/A 3.473±0.00 4.831±0.00 N/A N/A 9.117±0.00 10.955±0.00 5.798±4.11 0.470±0.00 N/A 6.213±0.00 N/A
ENST00000372407 7.145±0.00 2.485±0.00 N/A 8.531±7.58 31.051±0.00 12.007±0.00 0.356±0.14 15.219±0.00 29.185±0.00 6.699±4.92 N/A 4.413±1.92 26.455±0.00 7.373±0.00
ENST00000414879 7.820±0.00 N/A N/A 0.754±0.00 N/A N/A 0.107±0.00 N/A 1.524±0.00 N/A N/A 10.485±0.00 44.272±0.00 4.007±0.00
ENST00000429895 6.999±0.00 2.830±0.00 N/A N/A 28.855±0.00 7.066±0.00 0.378±0.00 6.806±0.00 14.154±0.00 9.698±0.00 0.254±0.00 11.977±10.44 20.782±4.73 4.437±2.30
ENST00000437607 N/A N/A N/A N/A 12.359±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000438120 N/A N/A 0.841±0.00 8.543±0.00 12.540±10.48 8.196±0.00 0.089±0.00 6.434±0.00 2.180±0.00 N/A 0.189±0.00 1.484±0.00 12.412±4.03 2.313±0.87
ENST00000477970 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.475±0.00 N/A N/A N/A
ENST00000496447 N/A 1.342±0.00 N/A N/A 2.794±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.025±0.00
ENST00000617451 N/A N/A N/A N/A N/A N/A 0.628±0.00 N/A N/A N/A 1.842±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005B6 CIL_0005B6_0002 CGP 1:43451003-43623666
CIL_0005B7 CIL_0005B7_0002 CGP 1:43525187-43705515

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005001 TAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0006470 IEA protein dephosphorylation
GO:0007155 IEA cell adhesion
GO:0007185 TAS transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0008201 IEA heparin binding
GO:0016311 IEA dephosphorylation
GO:0016477 IMP cell migration
GO:0016791 IEA phosphatase activity
GO:0032403 IEA protein complex binding
GO:0035335 IMP peptidyl-tyrosine dephosphorylation
GO:0070062 IDA extracellular vesicular exosome
GO:1900121 IMP negative regulation of receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005754 ptprfb protein tyrosine phosphatase, receptor type, f, b protein_coding Danio_rerio
ENSDARG00000076810 ptprfa protein tyrosine phosphatase, receptor type, f, a protein_coding Danio_rerio
ENSMUSG00000033295 Ptprf protein tyrosine phosphatase, receptor type, F protein_coding Mus_musculus

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