C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein pathway suppressor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169727 GPS1 9606 + 17:82050691-82057470 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306823 GPS1-004 82051909-82057470 protein_coding
  ENST00000320548 GPS1-003 82051875-82057470 protein_coding
  ENST00000392357 GPS1-007 82052570-82057470 retained_intron
  ENST00000392358 GPS1-006 82051958-82057470 protein_coding
  ENST00000578168 GPS1-024 82056524-82057470 protein_coding
  ENST00000578279 GPS1-023 82054952-82057117 retained_intron
  ENST00000578392 GPS1-019 82051908-82054542 nonsense_mediated_decay
  ENST00000578552 GPS1-001 82051865-82057470 protein_coding
  ENST00000578642 GPS1-015 82051898-82053785 retained_intron
  ENST00000580141 GPS1-016 82051901-82056019 nonsense_mediated_decay
  ENST00000580627 GPS1-018 82051902-82054682 nonsense_mediated_decay
  ENST00000580716 GPS1-010 82051477-82054741 protein_coding
  ENST00000580723 GPS1-021 82051927-82054738 nonsense_mediated_decay
  ENST00000581418 GPS1-017 82051901-82054668 protein_coding
  ENST00000581578 GPS1-013 82051897-82054542 protein_coding
  ENST00000582327 GPS1-008 82050948-82054651 protein_coding
  ENST00000583009 GPS1-022 82052233-82054569 protein_coding
  ENST00000583486 GPS1-025 82056524-82057470 retained_intron
  ENST00000583641 GPS1-012 82051897-82054757 protein_coding
  ENST00000583885 GPS1-014 82051897-82054559 protein_coding
  ENST00000583961 GPS1-011 82051500-82054586 protein_coding
  ENST00000583983 GPS1-026 82050691-82051837 processed_transcript
  ENST00000584229 GPS1-020 82051925-82053225 processed_transcript
  ENST00000584460 GPS1-005 82051929-82057463 nonsense_mediated_decay
  ENST00000585084 GPS1-009 82051175-82054968 protein_coding
  ENST00000623691 GPS1-028 82051897-82057470 protein_coding
  ENST00000623761 GPS1-029 82052242-82057424 protein_coding
  ENST00000624957 GPS1-027 82051893-82057440 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306823ENST00000320548ENST00000392358ENST00000578279ENST00000578552ENST00000580141ENST00000580716ENST00000581418ENST00000583486ENST00000583641ENST00000584460ENST00000585084ENST00000623691ENST00000623761
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306823 13.138±0.00 23.713±0.00 1.586±0.00 7.130±4.30 3.423±0.00 8.244±0.00 5.780±0.00 6.590±0.00 N/A 8.648±0.00 27.069±0.00 18.831±0.00 10.424±1.58 N/A
ENST00000320548 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.310±4.58
ENST00000392358 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.761±0.00 N/A N/A N/A
ENST00000578279 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.658±0.00 N/A N/A
ENST00000578552 18.862±0.00 14.746±0.00 N/A 6.532±3.79 28.137±0.00 10.948±0.00 7.904±6.03 36.639±0.00 13.580±10.37 14.180±0.00 32.663±25.12 21.264±8.79 23.552±9.51 35.839±0.00
ENST00000580141 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.549±0.00 N/A 16.840±0.00 21.962±0.00 32.681±0.00
ENST00000580716 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.562±0.00 22.224±0.00 N/A
ENST00000581418 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.268±0.00 N/A N/A N/A
ENST00000583486 N/A N/A N/A N/A 3.232±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000583641 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 43.759±0.00
ENST00000584460 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.780±0.00 N/A N/A N/A N/A
ENST00000585084 N/A N/A N/A N/A N/A N/A N/A N/A 3.687±0.00 N/A N/A N/A N/A N/A
ENST00000623691 N/A N/A 1.262±0.00 3.504±0.00 11.017±0.00 6.065±2.06 3.240±1.48 N/A N/A 9.995±0.00 34.255±0.00 9.708±5.49 15.097±4.91 21.452±0.00
ENST00000623761 N/A N/A N/A 7.377±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.910±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043X CIL_00043X_0002 CGP 17:82035136-82051831
CIL_0004VP CIL_0004VP_0001 CGP 17:82047902-82057470
CIL_0004VJ CIL_0004VJ_0001 CGP 17:82050691-82065887

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 TAS inactivation of MAPK activity
GO:0005095 TAS GTPase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007049 TAS cell cycle
GO:0007254 TAS JNK cascade
GO:0008180 IDA COP9 signalosome
GO:0010388 IDA cullin deneddylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040650 gps1 G protein pathway suppressor 1 protein_coding Danio_rerio
ENSMUSG00000025156 Gps1 G protein pathway suppressor 1 protein_coding Mus_musculus

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