C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM domain binding 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169744 LDB2 9606 - 4:16501541-16898809 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304523 LDB2-001 16501541-16898809 protein_coding
  ENST00000441778 LDB2-003 16501541-16898594 protein_coding
  ENST00000502640 LDB2-004 16501546-16898634 protein_coding
  ENST00000503153 LDB2-017 16512005-16653819 processed_transcript
  ENST00000503829 LDB2-018 16585976-16626993 processed_transcript
  ENST00000504189 LDB2-009 16750850-16898378 processed_transcript
  ENST00000504886 LDB2-015 16585950-16726502 processed_transcript
  ENST00000506732 LDB2-010 16585972-16898660 protein_coding
  ENST00000507464 LDB2-005 16502042-16595875 protein_coding
  ENST00000508804 LDB2-012 16588709-16759375 retained_intron
  ENST00000508918 LDB2-006 16502794-16898634 nonsense_mediated_decay
  ENST00000509803 LDB2-008 16501544-16507227 retained_intron
  ENST00000510825 LDB2-013 16741455-16898678 processed_transcript
  ENST00000512345 LDB2-014 16511985-16898621 nonsense_mediated_decay
  ENST00000513457 LDB2-011 16588710-16826560 processed_transcript
  ENST00000515064 LDB2-007 16501541-16898562 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000304523ENST00000441778ENST00000502640ENST00000506732ENST00000507464ENST00000508918ENST00000509803ENST00000510825ENST00000512345ENST00000513457ENST00000515064
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000304523 5.932±0.00 N/A N/A 7.864±2.69 1.949±0.00 3.606±0.00 1.458±0.78 N/A 1.016±0.00 17.286±0.00 N/A 1.128±0.00 N/A N/A
ENST00000441778 23.210±0.00 11.984±0.00 1.151±0.00 N/A 4.938±2.69 5.494±4.42 2.408±1.34 2.524±0.00 2.099±0.00 20.993±0.00 1.138±0.00 3.350±2.41 8.510±2.91 3.448±2.72
ENST00000502640 6.167±0.00 6.271±0.00 N/A 5.754±0.00 3.470±0.00 5.386±0.00 1.194±0.00 1.977±0.00 0.970±0.00 N/A 1.339±0.00 2.767±2.27 2.677±0.34 1.557±0.31
ENST00000506732 N/A N/A 8.941±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000507464 10.296±0.00 N/A N/A N/A N/A N/A 2.014±0.00 N/A N/A N/A 1.385±0.00 N/A N/A N/A
ENST00000508918 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.333±0.00 N/A N/A N/A
ENST00000509803 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.311±0.00 N/A N/A
ENST00000510825 N/A N/A 12.228±0.00 57.312±0.00 N/A 5.292±0.00 9.192±0.00 9.728±0.00 17.322±0.00 104.613±0.00 1.424±0.00 14.442±0.00 N/A N/A
ENST00000512345 N/A N/A N/A N/A N/A 1.508±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000513457 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.845±0.00 N/A N/A N/A
ENST00000515064 N/A N/A 1.631±0.00 8.072±0.15 1.843±0.00 3.885±0.00 N/A N/A N/A 9.548±0.00 1.491±0.00 5.233±0.00 4.510±2.73 1.954±0.95

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00033W CIL_00033W_0003 CGP 4:16160505-16898809
CIL_00033T CIL_00033T_0002 CGP 4:16501541-17512234

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000989 IEA transcription factor binding transcription factor activity
GO:0001942 IEA hair follicle development
GO:0003712 IEA transcription cofactor activity
GO:0005515 IEA protein binding
GO:0005634 IEA:IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0010669 IEA epithelial structure maintenance
GO:0019899 IEA enzyme binding
GO:0030274 IEA:ISS LIM domain binding
GO:0035019 IEA somatic stem cell maintenance
GO:0044089 IEA positive regulation of cellular component biogenesis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019579 ldb2a LIM-domain binding factor 2a protein_coding Danio_rerio
ENSDARG00000034896 ldb2b LIM-domain binding factor 2b protein_coding Danio_rerio
ENSMUSG00000039706 Ldb2 LIM domain binding 2 protein_coding Mus_musculus

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