C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185627 PSMD13 9606 + 11:236546-252984 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000352303 PSMD13-007 237026-252953 protein_coding
  ENST00000382671 PSMD13-002 237038-252981 nonsense_mediated_decay
  ENST00000431206 PSMD13-003 236977-252981 protein_coding
  ENST00000525665 PSMD13-004 237000-252966 nonsense_mediated_decay
  ENST00000526783 PSMD13-011 244429-252827 protein_coding
  ENST00000527047 PSMD13-005 237004-248197 retained_intron
  ENST00000527982 PSMD13-014 250784-252983 retained_intron
  ENST00000528906 PSMD13-009 236981-251611 protein_coding
  ENST00000529372 PSMD13-006 236966-248791 nonsense_mediated_decay
  ENST00000529679 PSMD13-013 251543-252617 retained_intron
  ENST00000532025 PSMD13-012 251227-252845 processed_transcript
  ENST00000532097 PSMD13-001 236546-252956 protein_coding
  ENST00000533717 PSMD13-010 248607-251894 retained_intron
  ENST00000534590 PSMD13-008 236977-247300 retained_intron
  ENST00000621534 PSMD13-201 236996-252984 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000352303ENST00000382671ENST00000525665ENST00000526783ENST00000528906ENST00000529679ENST00000532025ENST00000532097ENST00000533717ENST00000621534
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000352303 N/A N/A 2.631±0.00 13.503±9.42 12.186±9.19 8.211±5.83 6.054±4.23 11.736±4.65 8.119±5.85 12.367±8.81 16.231±14.76 20.161±14.42 13.676±0.00 20.399±0.00
ENST00000382671 27.420±0.00 51.889±0.00 N/A 4.096±0.00 32.782±0.00 9.814±0.00 7.752±5.86 14.726±9.34 11.221±8.06 21.041±0.00 14.681±9.47 22.778±12.84 46.875±14.71 20.759±0.69
ENST00000525665 N/A N/A 2.674±0.00 N/A N/A 3.415±0.00 N/A N/A N/A N/A 1.578±0.00 13.803±0.00 N/A N/A
ENST00000526783 28.236±0.00 51.802±0.00 N/A 26.880±0.00 N/A N/A N/A 17.221±0.00 N/A N/A N/A 63.008±0.00 54.194±0.00 29.652±0.66
ENST00000528906 N/A N/A N/A N/A N/A N/A 1.924±0.00 N/A 3.288±0.00 N/A N/A N/A N/A N/A
ENST00000529679 N/A N/A N/A N/A N/A 6.464±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000532025 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 49.590±0.00 33.530±0.00
ENST00000532097 N/A N/A N/A 2.299±0.00 N/A N/A N/A N/A N/A N/A N/A 12.141±0.00 N/A 13.755±0.00
ENST00000533717 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 34.006±0.00
ENST00000621534 12.669±0.00 N/A N/A N/A 3.035±0.00 15.382±0.00 9.034±0.00 N/A 7.795±6.52 9.534±7.90 32.995±0.00 13.781±0.00 20.496±9.48 14.118±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LA CIL_0006LA_0001 CGP 11:207511-236931
CIL_0006QN CIL_0006QN_0001 CGP 11:215458-252984

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005838 IEA proteasome regulatory particle
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007127 IEA meiosis I
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0022624 ISS proteasome accessory complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016239 psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 protein_coding Danio_rerio
ENSMUSG00000025487 Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 protein_coding Mus_musculus

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