C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019647 Sema6a 10090 - 18:47235598-47368870 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019791 Sema6a-001 47245254-47368830 protein_coding
  ENSMUST00000076043 Sema6a-003 47247438-47368446 protein_coding
  ENSMUST00000115449 Sema6a-201 47245255-47368868 protein_coding
  ENSMUST00000123228 Sema6a-010 47235598-47281195 protein_coding
  ENSMUST00000126684 Sema6a-008 47291894-47333326 protein_coding
  ENSMUST00000135790 Sema6a-004 47247440-47368448 protein_coding
  ENSMUST00000141224 Sema6a-005 47275643-47368868 retained_intron
  ENSMUST00000144223 Sema6a-009 47303674-47368268 retained_intron
  ENSMUST00000151382 Sema6a-006 47275658-47368870 retained_intron
  ENSMUST00000156422 Sema6a-007 47248383-47333348 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000019791ENSMUST00000076043ENSMUST00000115449ENSMUST00000126684ENSMUST00000135790ENSMUST00000156422
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000019791 0.463±0.08 N/A 0.712±0.00 4.665±2.14 N/A N/A 0.816±0.00 N/A 0.431±0.04 N/A 0.447±0.11 0.740±0.37 2.022±0.76 0.064±0.06
ENSMUST00000076043 1.859±0.69 0.984±0.00 0.597±0.18 5.525±2.87 1.370±0.62 2.315±0.03 1.213±0.18 1.258±0.35 0.597±0.33 5.787±2.77 0.510±0.11 1.730±0.46 5.640±2.42 0.167±0.10
ENSMUST00000115449 1.462±0.04 1.267±0.24 0.255±0.00 1.687±0.77 0.691±0.05 1.004±0.26 N/A N/A N/A N/A N/A 0.656±0.36 0.528±0.00 N/A
ENSMUST00000126684 N/A N/A N/A 5.919±0.00 N/A N/A N/A N/A N/A N/A N/A 3.184±0.00 15.731±4.78 0.166±0.00
ENSMUST00000135790 0.700±0.00 N/A 0.704±0.00 4.121±2.11 0.402±0.08 N/A N/A 0.488±0.00 0.338±0.04 6.054±0.16 0.305±0.13 0.927±0.13 2.743±0.92 0.228±0.09
ENSMUST00000156422 2.116±0.79 1.213±0.12 N/A 1.196±0.00 1.151±0.46 2.313±0.40 0.752±0.03 1.174±0.00 N/A 6.290±1.10 0.235±0.00 1.458±0.34 N/A 0.207±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004L9 CIL_0004L9_0002 CGP 18:46958862-47368870

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IMP neuron migration
GO:0004872 IEA receptor activity
GO:0004888 IMP transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006915 NAS apoptotic process
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0007411 NAS axon guidance
GO:0016020 NAS membrane
GO:0016021 IEA integral component of membrane
GO:0030215 IPI semaphorin receptor binding
GO:0030424 NAS axon
GO:0051642 IMP centrosome localization
GO:0071526 IMP semaphorin-plexin signaling pathway
GO:2001224 IMP positive regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043028 sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A protein_coding Danio_rerio
ENSG00000092421 SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A protein_coding Homo_sapiens

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