C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020167 Tcf3 10090 - 10:80409514-80433647 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020377 Tcf3-004 80409608-80433621 protein_coding
  ENSMUST00000020379 Tcf3-011 80409626-80433635 protein_coding
  ENSMUST00000105339 Tcf3-008 80410054-80431082 protein_coding
  ENSMUST00000105340 Tcf3-003 80409626-80433635 protein_coding
  ENSMUST00000105341 Tcf3-009 80409620-80431012 protein_coding
  ENSMUST00000105342 Tcf3-006 80409547-80433643 protein_coding
  ENSMUST00000105343 Tcf3-007 80409547-80433647 protein_coding
  ENSMUST00000105344 Tcf3-005 80409514-80433637 protein_coding
  ENSMUST00000105345 Tcf3-002 80409514-80433647 protein_coding
  ENSMUST00000105346 Tcf3-001 80409608-80433621 protein_coding
  ENSMUST00000127931 Tcf3-013 80415243-80416288 retained_intron
  ENSMUST00000129027 Tcf3-012 80412627-80415487 processed_transcript
  ENSMUST00000156244 Tcf3-014 80420083-80421860 protein_coding
  ENSMUST00000156990 Tcf3-010 80410054-80430985 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020377ENSMUST00000020379ENSMUST00000105339ENSMUST00000105340ENSMUST00000105341ENSMUST00000105342ENSMUST00000105343ENSMUST00000105344ENSMUST00000105345ENSMUST00000105346ENSMUST00000156990
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020377 11.319±0.00 N/A N/A N/A 9.771±0.00 5.277±0.00 N/A N/A 1.090±0.00 N/A 1.396±0.26 12.122±0.00 3.198±0.00 1.303±0.09
ENSMUST00000020379 14.796±7.39 11.191±1.31 6.780±1.44 10.392±5.74 15.751±8.37 9.333±3.18 4.520±1.33 5.214±2.04 12.110±7.00 14.545±3.67 2.203±0.60 25.423±5.36 7.206±2.05 2.986±0.29
ENSMUST00000105339 5.636±0.00 N/A N/A 13.427±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000105340 N/A 8.967±2.32 N/A N/A N/A 7.937±0.00 N/A N/A N/A N/A N/A 12.060±0.00 N/A 1.017±0.00
ENSMUST00000105341 N/A N/A N/A 3.369±0.00 N/A N/A N/A N/A N/A N/A 1.803±0.00 30.964±0.00 8.464±4.21 0.909±0.00
ENSMUST00000105342 N/A 6.176±0.65 2.735±0.00 14.078±3.17 9.505±0.00 5.299±0.31 N/A 2.410±0.46 5.186±4.18 5.166±0.00 1.075±0.43 12.755±0.60 2.588±0.00 N/A
ENSMUST00000105343 N/A 9.139±3.20 2.352±0.18 N/A 9.270±0.00 6.715±0.40 N/A 2.816±0.00 7.355±3.40 6.673±0.00 1.409±0.41 15.272±6.10 4.569±1.14 1.203±0.00
ENSMUST00000105344 N/A 8.306±0.00 N/A N/A 8.709±0.00 N/A N/A 2.321±0.00 1.442±0.00 N/A N/A N/A 3.352±0.00 N/A
ENSMUST00000105345 N/A 6.225±0.00 2.794±0.00 4.978±0.00 N/A 7.223±0.00 N/A N/A 7.179±5.42 N/A 0.816±0.00 8.244±1.03 N/A N/A
ENSMUST00000105346 8.503±0.00 N/A 3.181±0.13 10.811±0.13 N/A N/A 0.933±0.00 2.280±0.00 4.422±0.28 N/A 1.494±0.82 6.067±0.00 N/A N/A
ENSMUST00000156990 5.541±0.00 13.611±0.00 N/A N/A 10.682±2.42 N/A 2.705±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004BR CIL_0004BR_0002 CGP 10:80402997-80433647
CIL_000188 CIL_000188_0002 CGP 10:80409514-80517276

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000788 IDA nuclear nucleosome
GO:0000790 IEA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IMP RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001205 IMP RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001779 IGI natural killer cell differentiation
GO:0002326 ISS B cell lineage commitment
GO:0003677 ISS DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003713 ISS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007369 IGI gastrulation
GO:0008134 ISS transcription factor binding
GO:0010628 IMP positive regulation of gene expression
GO:0030098 IMP lymphocyte differentiation
GO:0030890 ISS positive regulation of B cell proliferation
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0032496 IMP response to lipopolysaccharide
GO:0033077 IMP T cell differentiation in thymus
GO:0033152 IMP immunoglobulin V(D)J recombination
GO:0042493 IMP response to drug
GO:0042803 ISS protein homodimerization activity
GO:0043234 ISS protein complex
GO:0043425 IEA bHLH transcription factor binding
GO:0043565 IGI sequence-specific DNA binding
GO:0043966 IMP histone H3 acetylation
GO:0043967 IMP histone H4 acetylation
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045787 ISS positive regulation of cell cycle
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048468 IGI cell development
GO:0048541 IGI Peyer's patch development
GO:0050821 IDA protein stabilization
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070491 IEA repressing transcription factor binding
GO:0070644 IEA vitamin D response element binding
GO:0070888 IDA E-box binding
GO:2000045 ISS regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005915 tcf3a transcription factor 3a protein_coding Danio_rerio
ENSDARG00000052383 tcf3b transcription factor 3b protein_coding Danio_rerio
ENSG00000071564 TCF3 transcription factor 3 protein_coding Homo_sapiens

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