C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transcription factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020379 Tcf3-011 ENSMUSG00000020167 10090 - 10:80409626-80433635 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020379
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020379 14.796±7.39 11.191±1.31 6.780±1.44 10.392±5.74 15.751±8.37 9.333±3.18 4.520±1.33 5.214±2.04 12.110±7.00 14.545±3.67 2.203±0.60 25.423±5.36 7.206±2.05 2.986±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004BR CIL_0004BR_0002 CGP 10:80402997-80433647
CIL_000188 CIL_000188_0002 CGP 10:80409514-80517276

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000788 IDA nuclear nucleosome
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IMP RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001205 IMP RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001779 IGI natural killer cell differentiation
GO:0002326 ISS B cell lineage commitment
GO:0003677 ISS DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003713 ISS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007369 IGI gastrulation
GO:0008134 ISS transcription factor binding
GO:0010628 IMP positive regulation of gene expression
GO:0030098 IMP lymphocyte differentiation
GO:0030890 ISS positive regulation of B cell proliferation
GO:0032496 IMP response to lipopolysaccharide
GO:0033077 IMP T cell differentiation in thymus
GO:0033152 IMP immunoglobulin V(D)J recombination
GO:0042493 IMP response to drug
GO:0042803 ISS protein homodimerization activity
GO:0043234 ISS protein complex
GO:0043565 IGI sequence-specific DNA binding
GO:0043966 IMP histone H3 acetylation
GO:0043967 IMP histone H4 acetylation
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045787 ISS positive regulation of cell cycle
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048468 IGI cell development
GO:0048541 IGI Peyer's patch development
GO:0050821 IDA protein stabilization
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070888 IDA E-box binding
GO:2000045 ISS regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000078298 tcf3a-202 protein_coding Danio_rerio 0 207
ENSDART00000130136 tcf3b-202 protein_coding Danio_rerio 1.4013e-45 189
ENSDART00000074228 tcf3b-201 protein_coding Danio_rerio 1.4013e-45 189
ENSDART00000020529 tcf3a-201 protein_coding Danio_rerio 8e-33 147
ENST00000262965 TCF3-201 protein_coding Homo_sapiens 0 1408
ENST00000344749 TCF3-202 protein_coding Homo_sapiens 0 1378
ENST00000395423 TCF3-003 protein_coding Homo_sapiens 0 905
ENST00000453954 TCF3-008 protein_coding Homo_sapiens 0 1360
ENST00000585731 TCF3-005 protein_coding Homo_sapiens 0 527
ENST00000585855 TCF3-015 nonsense_mediated_decay Homo_sapiens 0 477
ENST00000586318 TCF3-007 protein_coding Homo_sapiens 0 267
ENST00000587235 TCF3-017 protein_coding Homo_sapiens 0 553
ENST00000588136 TCF3-002 protein_coding Homo_sapiens 0 1642
ENST00000590436 TCF3-009 protein_coding Homo_sapiens 0 612
ENST00000590605 TCF3-018 retained_intron Homo_sapiens 0 407
ENST00000590684 TCF3-004 protein_coding Homo_sapiens 0 658
ENST00000592395 TCF3-012 nonsense_mediated_decay Homo_sapiens 0 477
ENST00000610756 TCF3-010 retained_intron Homo_sapiens 0 821
ENST00000611869 TCF3-001 protein_coding Homo_sapiens 0 1408

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