C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: misshapen-like kinase 1 (zebrafish)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020827 Mink1 10090 + 11:70562881-70614483 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072237 Mink1-201 70562881-70614482 protein_coding
  ENSMUST00000072873 Mink1-006 70562890-70614128 protein_coding
  ENSMUST00000079244 Mink1-003 70563017-70614483 protein_coding
  ENSMUST00000102558 Mink1-005 70563070-70613712 protein_coding
  ENSMUST00000102559 Mink1-007 70562898-70614478 protein_coding
  ENSMUST00000132208 Mink1-008 70610051-70610979 retained_intron
  ENSMUST00000133310 Mink1-002 70598988-70605031 processed_transcript
  ENSMUST00000136663 Mink1-004 70601989-70614483 protein_coding
  ENSMUST00000142650 Mink1-009 70609738-70610709 retained_intron
  ENSMUST00000149845 Mink1-001 70604223-70607079 nonsense_mediated_decay
  ENSMUST00000152857 Mink1-010 70607812-70608828 retained_intron
  ENSMUST00000153503 Mink1-011 70606701-70607773 retained_intron
  ENSMUST00000178764 Mink1-013 70604200-70607424 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072237ENSMUST00000072873ENSMUST00000079244ENSMUST00000102558ENSMUST00000102559ENSMUST00000136663
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072237 2.029±0.00 6.962±1.99 N/A N/A 12.456±1.41 10.405±2.54 N/A 6.262±0.00 3.010±0.99 10.088±0.67 N/A 7.014±0.00 N/A N/A
ENSMUST00000072873 7.574±0.70 7.421±1.55 16.583±0.67 5.978±0.00 10.249±2.67 15.885±3.14 3.421±0.88 9.759±2.32 5.965±1.55 16.858±1.09 1.935±0.37 11.407±4.02 7.292±0.33 1.979±0.49
ENSMUST00000079244 N/A N/A N/A N/A N/A N/A N/A 4.565±1.37 1.846±0.47 7.700±0.00 N/A 6.453±0.00 2.437±1.31 N/A
ENSMUST00000102558 N/A N/A N/A 42.379±0.00 5.913±0.00 N/A 1.867±0.00 N/A N/A N/A 1.730±0.08 12.748±4.81 4.390±1.22 2.434±1.13
ENSMUST00000102559 4.405±0.77 4.271±0.88 7.201±1.03 32.185±23.07 2.670±0.00 N/A 4.904±0.43 5.559±0.72 1.457±0.13 9.460±0.42 3.701±1.63 6.366±1.81 3.334±0.59 3.545±1.12
ENSMUST00000136663 4.504±1.27 3.588±0.05 6.635±0.57 7.797±0.00 7.436±1.47 6.631±1.19 2.074±0.32 6.223±2.04 4.531±1.27 8.273±0.00 1.815±0.85 9.183±2.17 3.893±1.62 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001RG CIL_0001RG_0002 CGP 11:70540064-70614483
CIL_0001R8 CIL_0001R8_0002 CGP 11:70562881-70619216

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001952 IEA regulation of cell-matrix adhesion
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0006468 IEA protein phosphorylation
GO:0006950 IDA response to stress
GO:0007268 ISS synaptic transmission
GO:0007275 IEP multicellular organismal development
GO:0022407 IEA regulation of cell-cell adhesion
GO:0030054 IEA cell junction
GO:0030334 IEA regulation of cell migration
GO:0031532 IEA actin cytoskeleton reorganization
GO:0035556 IDA intracellular signal transduction
GO:0042995 IEA cell projection
GO:0045060 IMP negative thymic T cell selection
GO:0045211 IEA postsynaptic membrane
GO:0046330 IEA positive regulation of JNK cascade
GO:0046777 IEA protein autophosphorylation
GO:0048813 ISS dendrite morphogenesis
GO:0050790 IEA regulation of catalytic activity
GO:0070062 IEA extracellular vesicular exosome
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035360 mink1 misshapen-like kinase 1 protein_coding Danio_rerio
ENSG00000141503 MINK1 misshapen-like kinase 1 protein_coding Homo_sapiens

Loading