C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024454 Hdac3 10090 - 18:37935844-37954988 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043498 Hdac3-001 37936972-37954988 protein_coding
  ENSMUST00000143660 Hdac3-003 37935844-37945564 retained_intron
  ENSMUST00000144471 Hdac3-004 37936972-37944075 retained_intron
  ENSMUST00000153945 Hdac3-002 37936978-37954931 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043498ENSMUST00000144471ENSMUST00000153945
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043498 13.498±0.61 25.830±2.04 13.131±2.85 36.488±20.26 37.720±16.93 8.230±1.98 8.148±1.37 9.091±0.85 8.387±4.11 7.035±2.76 14.939±1.89 22.906±15.04 21.668±8.99 7.995±3.81
ENSMUST00000144471 N/A 10.590±1.44 6.859±0.92 7.079±3.75 10.017±2.22 6.113±0.25 3.666±0.40 N/A 4.039±0.18 4.971±0.69 4.062±0.00 9.393±3.28 4.560±0.00 N/A
ENSMUST00000153945 N/A N/A N/A 20.827±0.00 N/A N/A N/A N/A N/A N/A N/A 21.588±0.00 20.514±1.87 6.076±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006QD CIL_0006QD_0002 CGP 18:37843601-37954988
CIL_0006QE CIL_0006QE_0002 CGP 18:37935844-37959179

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003714 ISS transcription corepressor activity
GO:0004407 TAS histone deacetylase activity
GO:0005515 IPI protein binding
GO:0005634 IDA:TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005876 IEA spindle microtubule
GO:0006351 IEA transcription, DNA-templated
GO:0006476 IEA protein deacetylation
GO:0007346 IDA regulation of mitotic cell cycle
GO:0008134 TAS transcription factor binding
GO:0016568 TAS chromatin modification
GO:0016575 IMP histone deacetylation
GO:0017053 ISS transcriptional repressor complex
GO:0019899 IEA enzyme binding
GO:0030332 IEA cyclin binding
GO:0031490 IDA chromatin DNA binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032922 IGI circadian regulation of gene expression
GO:0033558 IEA protein deacetylase activity
GO:0040014 IGI regulation of multicellular organism growth
GO:0042826 IEA histone deacetylase binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046329 IEA negative regulation of JNK cascade
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0051225 IEA spindle assembly
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037514 hdac3 histone deacetylase 3 protein_coding Danio_rerio
ENSG00000171720 HDAC3 histone deacetylase 3 protein_coding Homo_sapiens

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