C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025917 Cops5 10090 - 1:10024601-10038168 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027050 Cops5-001 10024601-10038127 protein_coding
  ENSMUST00000139578 Cops5-003 10030920-10037938 retained_intron
  ENSMUST00000150509 Cops5-002 10033040-10038168 retained_intron
  ENSMUST00000186528 Cops5-006 10027198-10037941 nonsense_mediated_decay
  ENSMUST00000188619 Cops5-005 10030687-10038149 protein_coding
  ENSMUST00000190155 Cops5-007 10024843-10035128 nonsense_mediated_decay
  ENSMUST00000191296 Cops5-004 10037280-10037945 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027050ENSMUST00000139578ENSMUST00000186528ENSMUST00000190155
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027050 12.060±1.97 N/A 27.250±4.07 28.298±10.92 5.124±2.10 3.529±0.00 7.483±2.36 8.535±1.60 17.762±13.31 5.801±1.48 57.072±1.89 14.125±12.69 30.977±9.61 32.931±2.61
ENSMUST00000139578 N/A 2.704±0.53 N/A N/A 2.708±0.90 2.583±0.00 N/A N/A N/A 3.375±0.57 N/A 3.511±0.60 N/A N/A
ENSMUST00000186528 28.098±1.38 17.732±3.47 22.755±2.17 47.743±3.67 16.893±6.99 16.850±3.24 17.761±1.71 16.280±2.06 20.907±4.88 13.087±1.34 N/A 18.668±6.64 22.734±0.00 58.617±3.10
ENSMUST00000190155 N/A N/A N/A 43.042±0.00 10.328±4.59 9.768±1.36 8.629±0.96 10.931±1.35 11.407±1.39 8.119±0.00 N/A 30.857±23.67 93.578±8.51 43.164±14.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003BC CIL_0003BC_0002 CGP 1:9968624-10038168
CIL_0003BF CIL_0003BF_0002 CGP 1:10024601-10136768

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000338 IEA protein deneddylation
GO:0003713 TAS transcription coactivator activity
GO:0004843 IEA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 TAS transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006508 IEA proteolysis
GO:0008021 IEA synaptic vesicle
GO:0008180 IDA COP9 signalosome
GO:0008237 IEA metallopeptidase activity
GO:0010388 IEA cullin deneddylation
GO:0016579 IEA protein deubiquitination
GO:0030054 IEA cell junction
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046328 IEA regulation of JNK cascade
GO:0046872 IEA metal ion binding
GO:0051726 IMP regulation of cell cycle
GO:1990182 IEA exosomal secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057624 cops5 COP9 constitutive photomorphogenic homolog subunit 5 protein_coding Danio_rerio
ENSG00000121022 COPS5 COP9 signalosome subunit 5 protein_coding Homo_sapiens

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