C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: STE20-related kinase adaptor beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026027 Stradb 10090 + 1:58973522-58995715 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027185 Stradb-001 58973522-58995715 protein_coding
  ENSMUST00000114296 Stradb-004 58973522-58991512 protein_coding
  ENSMUST00000123301 Stradb-002 58973522-58994997 nonsense_mediated_decay
  ENSMUST00000123965 Stradb-006 58973522-58981475 retained_intron
  ENSMUST00000147637 Stradb-005 58973522-58987847 retained_intron
  ENSMUST00000152318 Stradb-008 58991058-58994359 protein_coding
  ENSMUST00000153990 Stradb-003 58973522-58995122 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027185ENSMUST00000114296ENSMUST00000123301ENSMUST00000147637ENSMUST00000152318ENSMUST00000153990
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027185 3.807±0.77 N/A 0.632±0.07 3.552±1.18 2.929±0.81 1.526±0.34 3.482±1.48 3.569±0.88 2.948±1.00 1.319±0.65 4.984±0.00 1.861±0.47 1.491±0.30 2.300±0.40
ENSMUST00000114296 N/A 16.861±3.93 1.260±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 4.286±1.30 2.368±0.00 N/A
ENSMUST00000123301 7.228±2.03 6.618±1.25 3.588±1.00 10.601±5.08 8.588±2.40 5.113±0.97 11.114±1.24 10.848±1.53 10.934±2.75 4.333±0.70 20.241±1.81 5.226±1.48 6.045±3.44 3.974±1.55
ENSMUST00000147637 N/A N/A N/A 0.588±0.00 N/A N/A N/A N/A N/A N/A N/A 0.591±0.21 N/A 0.151±0.00
ENSMUST00000152318 N/A N/A N/A 11.153±0.00 N/A N/A N/A N/A N/A N/A N/A 5.776±0.00 9.953±0.00 N/A
ENSMUST00000153990 N/A N/A 1.883±0.65 6.354±0.16 2.137±0.00 N/A 2.866±0.18 N/A 3.790±0.86 N/A 22.256±2.96 1.919±0.17 3.187±2.29 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089O CIL_00089O_0002 VISTA 1:58652904-59256413
CIL_0000JJ CIL_0000JJ_0003 CGP 1:58900449-58995715
CIL_00020Q CIL_00020Q_0002 CGP 1:58973522-59094900

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IDA cell morphogenesis
GO:0004672 IDA protein kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0006611 ISS protein export from nucleus
GO:0007010 TAS cytoskeleton organization
GO:0007049 IEA cell cycle
GO:0007254 IDA JNK cascade
GO:0032147 ISS activation of protein kinase activity
GO:2001240 IDA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088225 STRADB STE20-related kinase adaptor beta protein_coding Danio_rerio
ENSG00000082146 STRADB STE20-related kinase adaptor beta protein_coding Homo_sapiens

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