C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5'-3' exoribonuclease 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027433 Xrn2 10090 + 2:147012996-147078000 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028921 Xrn2-001 147012996-147078000 protein_coding
  ENSMUST00000136136 Xrn2-003 147042546-147047822 retained_intron
  ENSMUST00000137358 Xrn2-004 147061440-147068900 retained_intron
  ENSMUST00000147057 Xrn2-002 147029552-147038287 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028921ENSMUST00000137358ENSMUST00000147057
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028921 7.458±1.98 2.801±0.86 15.858±1.63 15.664±7.48 6.124±1.54 4.581±1.08 3.538±0.48 5.883±0.50 9.748±5.82 7.628±1.32 3.628±0.22 11.268±10.52 18.332±6.88 11.947±1.87
ENSMUST00000137358 N/A 3.904±0.29 N/A N/A N/A 8.000±1.18 N/A N/A 7.306±0.00 N/A N/A N/A N/A N/A
ENSMUST00000147057 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 30.492±0.00 43.586±0.00 50.204±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007P1 CIL_0007P1_0008 UCNEbase 2:146325178-147069451
CIL_00097L CIL_00097L_0002 VISTA 2:146657766-147260813
CIL_0002ZA CIL_0002ZA_0002 CGP 2:146855864-147078000
CIL_0008VN CIL_0008VN_0002 VISTA 2:146880290-147481581
CIL_0003QC CIL_0003QC_0002 CGP 2:147012996-147085445

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000738 ISS DNA catabolic process, exonucleolytic
GO:0004534 NAS 5'-3' exoribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005730 ISS nucleolus
GO:0006281 NAS DNA repair
GO:0006310 NAS DNA recombination
GO:0006353 IEA DNA-templated transcription, termination
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0007017 TAS microtubule-based process
GO:0007283 IEP spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0008409 ISS 5'-3' exonuclease activity
GO:0016020 IEA membrane
GO:0016049 IGI cell growth
GO:0016070 IGI RNA metabolic process
GO:0016235 IEA aggresome
GO:0044822 IEA poly(A) RNA binding
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069092 xrn2 5'-3' exoribonuclease 2 protein_coding Danio_rerio
ENSG00000088930 XRN2 5'-3' exoribonuclease 2 protein_coding Homo_sapiens

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