C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neutral sphingomyelinase (N-SMase) activation associated factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028245 Nsmaf 10090 - 4:6396207-6454271 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029910 Nsmaf-001 6396207-6454271 protein_coding
  ENSMUST00000124344 Nsmaf-011 6433272-6454097 protein_coding
  ENSMUST00000124656 Nsmaf-008 6437913-6444393 processed_transcript
  ENSMUST00000143566 Nsmaf-003 6406400-6454255 processed_transcript
  ENSMUST00000143704 Nsmaf-002 6396207-6454271 retained_intron
  ENSMUST00000143983 Nsmaf-009 6424570-6432698 retained_intron
  ENSMUST00000145399 Nsmaf-005 6429729-6446327 processed_transcript
  ENSMUST00000149015 Nsmaf-010 6396411-6399006 retained_intron
  ENSMUST00000156078 Nsmaf-004 6409019-6423988 retained_intron
  ENSMUST00000156283 Nsmaf-007 6428450-6453579 processed_transcript
  ENSMUST00000156715 Nsmaf-006 6396769-6454096 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029910ENSMUST00000149015
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029910 11.441±3.61 10.962±2.23 20.144±3.08 10.839±2.18 15.630±1.41 7.669±1.65 11.045±1.97 9.002±0.48 10.822±7.76 15.237±1.41 10.901±2.63 22.434±2.79 9.794±0.80 3.016±0.92
ENSMUST00000149015 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.947±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001T7 CIL_0001T7_0002 CGP 4:6265612-6408423
CIL_0002RG CIL_0002RG_0002 CGP 4:6365650-6454271
CIL_0001SZ CIL_0001SZ_0002 CGP 4:6396207-6991557

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005123 TAS death receptor binding
GO:0016230 IEA sphingomyelin phosphodiesterase activator activity
GO:0043065 IEA positive regulation of apoptotic process
GO:0043085 IEA positive regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051920 nsmaf neutral sphingomyelinase (N-SMase) activation associated factor protein_coding Danio_rerio
ENSG00000035681 NSMAF neutral sphingomyelinase (N-SMase) activation associated factor protein_coding Homo_sapiens

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