C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032187 Smarca4 10090 + 9:21616169-21704230 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034707 Smarca4-001 21616169-21704217 protein_coding
  ENSMUST00000098948 Smarca4-201 21616169-21704230 protein_coding
  ENSMUST00000172996 Smarca4-002 21635767-21686228 protein_coding
  ENSMUST00000174008 Smarca4-003 21616264-21703366 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034707ENSMUST00000098948ENSMUST00000172996ENSMUST00000174008
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034707 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.069±0.00
ENSMUST00000098948 N/A 3.661±0.58 4.146±0.00 15.850±3.98 2.115±0.28 2.464±0.46 0.954±0.00 1.657±0.01 1.963±1.36 1.929±0.00 1.177±0.13 7.207±6.09 12.821±7.33 2.797±0.00
ENSMUST00000172996 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.528±0.00 N/A 9.628±5.18
ENSMUST00000174008 15.566±3.39 22.713±4.83 17.562±0.79 48.783±9.98 15.466±5.60 18.055±2.16 7.861±0.38 9.981±0.57 9.737±3.93 16.635±2.56 6.359±0.66 30.456±6.35 24.491±11.92 18.869±1.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002S7 CIL_0002S7_0002 CGP 9:21592722-21704230
CIL_00058P CIL_00058P_0004 CGP 9:21616169-21749916

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000792 IDA heterochromatin
GO:0000902 IMP cell morphogenesis
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001105 IEA RNA polymerase II transcription coactivator activity
GO:0001570 IMP vasculogenesis
GO:0001701 IMP in utero embryonic development
GO:0001832 IMP blastocyst growth
GO:0001835 IMP blastocyst hatching
GO:0001889 IMP liver development
GO:0002039 IEA p53 binding
GO:0003407 IEA neural retina development
GO:0003682 IDA chromatin binding
GO:0003713 IEA transcription coactivator activity
GO:0003714 ISS transcription corepressor activity
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005719 IDA nuclear euchromatin
GO:0005726 IDA perichromatin fibrils
GO:0005730 IEA nucleolus
GO:0006200 IEA ATP catabolic process
GO:0006334 TAS nucleosome assembly
GO:0006337 IEA nucleosome disassembly
GO:0006338 IMP chromatin remodeling
GO:0006346 IDA methylation-dependent chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0007399 IMP nervous system development
GO:0007403 IMP glial cell fate determination
GO:0007507 IMP heart development
GO:0008094 IEA DNA-dependent ATPase activity
GO:0008134 IPI transcription factor binding
GO:0010424 IMP DNA methylation on cytosine within a CG sequence
GO:0016020 IEA membrane
GO:0016514 TAS SWI/SNF complex
GO:0016887 TAS ATPase activity
GO:0019827 IMP stem cell maintenance
GO:0022008 IDA neurogenesis
GO:0030198 IMP extracellular matrix organization
GO:0030216 IMP keratinocyte differentiation
GO:0030308 IEA negative regulation of cell growth
GO:0030900 IMP forebrain development
GO:0030902 IMP hindbrain development
GO:0030957 IEA Tat protein binding
GO:0031492 IEA nucleosomal DNA binding
GO:0035116 IMP embryonic hindlimb morphogenesis
GO:0035887 IMP aortic smooth muscle cell differentiation
GO:0043044 IEA ATP-dependent chromatin remodeling
GO:0043234 IEA protein complex
GO:0043388 IGI positive regulation of DNA binding
GO:0043923 IEA positive regulation by host of viral transcription
GO:0043966 IMP histone H3 acetylation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0047485 IEA protein N-terminus binding
GO:0048562 IMP embryonic organ morphogenesis
GO:0048730 IMP epidermis morphogenesis
GO:0050681 IEA androgen receptor binding
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060318 IMP definitive erythrocyte differentiation
GO:0060347 IGI heart trabecula formation
GO:0060766 IEA negative regulation of androgen receptor signaling pathway
GO:0070307 IMP lens fiber cell development
GO:0070577 IEA lysine-acetylated histone binding
GO:0071564 IDA npBAF complex
GO:0071565 IDA nBAF complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008350 SMARCA4 (1 of 2) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 protein_coding Danio_rerio
ENSDARG00000077226 smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 protein_coding Danio_rerio
ENSG00000127616 SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 protein_coding Homo_sapiens

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