C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: scavenger receptor class B, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037936 Scarb1 10090 - 5:125277087-125341094 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086075 Scarb1-001 125277087-125341094 protein_coding
  ENSMUST00000111390 Scarb1-002 125277089-125341071 protein_coding
  ENSMUST00000123338 Scarb1-009 125297319-125304542 processed_transcript
  ENSMUST00000124582 Scarb1-010 125277787-125284159 processed_transcript
  ENSMUST00000127148 Scarb1-005 125277566-125294109 protein_coding
  ENSMUST00000133624 Scarb1-008 125300360-125316632 processed_transcript
  ENSMUST00000135736 Scarb1-004 125282950-125286677 retained_intron
  ENSMUST00000137783 Scarb1-006 125304179-125340008 protein_coding
  ENSMUST00000148373 Scarb1-003 125283355-125341019 retained_intron
  ENSMUST00000156532 Scarb1-007 125304249-125326267 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086075ENSMUST00000111390ENSMUST00000123338ENSMUST00000148373
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086075 65.684±19.37 1048.744±57.86 31.488±0.57 3.700±0.04 74.840±8.82 20.530±2.38 10.345±4.35 10.477±2.82 53.431±13.74 61.359±10.91 6.303±0.99 346.004±70.03 52.519±33.37 18.016±9.23
ENSMUST00000111390 38.117±8.47 257.863±10.16 6.590±0.19 6.865±1.76 46.004±6.80 4.153±0.49 8.798±0.32 4.390±0.76 26.196±8.61 24.760±3.06 3.636±0.99 104.881±19.06 18.811±8.93 37.536±25.15
ENSMUST00000123338 N/A N/A N/A 6.055±0.00 N/A N/A N/A N/A N/A N/A N/A 159.218±0.00 65.128±50.10 9.473±0.00
ENSMUST00000148373 N/A N/A N/A 4.822±0.00 N/A N/A N/A N/A N/A N/A N/A 73.969±14.35 N/A 7.609±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000399 CIL_000399_0002 CGP 5:125017153-125341094
CIL_00006N CIL_00006N_0003 CGP 5:125277087-125390202

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IEA lipopolysaccharide binding
GO:0001875 IEA lipopolysaccharide receptor activity
GO:0001935 IMP endothelial cell proliferation
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005765 IEA lysosomal membrane
GO:0005886 ISS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005901 IDA caveola
GO:0006702 IEA androgen biosynthetic process
GO:0006707 IMP cholesterol catabolic process
GO:0006869 IEA lipid transport
GO:0006898 IEA receptor-mediated endocytosis
GO:0006910 IEA phagocytosis, recognition
GO:0007155 IEA cell adhesion
GO:0008035 IDA high-density lipoprotein particle binding
GO:0009986 IEA cell surface
GO:0010867 IMP positive regulation of triglyceride biosynthetic process
GO:0010886 ISS positive regulation of cholesterol storage
GO:0010899 IMP regulation of phosphatidylcholine catabolic process
GO:0015914 IMP phospholipid transport
GO:0015920 IEA lipopolysaccharide transport
GO:0016021 IDA integral component of membrane
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 IMP cholesterol transport
GO:0031528 IEA microvillus membrane
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032497 IEA detection of lipopolysaccharide
GO:0033344 IDA cholesterol efflux
GO:0034185 IPI apolipoprotein binding
GO:0034186 IEA apolipoprotein A-I binding
GO:0034375 IMP high-density lipoprotein particle remodeling
GO:0034383 IMP low-density lipoprotein particle clearance
GO:0034384 ISS high-density lipoprotein particle clearance
GO:0042632 IMP cholesterol homeostasis
GO:0042803 IEA protein homodimerization activity
GO:0043534 IMP blood vessel endothelial cell migration
GO:0043654 ISS recognition of apoptotic cell
GO:0043691 IMP reverse cholesterol transport
GO:0044406 IEA adhesion of symbiont to host
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0070328 IMP triglyceride homeostasis
GO:0070506 ISS high-density lipoprotein particle receptor activity
GO:0070508 IDA cholesterol import

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042697 scarb1 scavenger receptor class B, member 1 protein_coding Danio_rerio
ENSG00000073060 SCARB1 scavenger receptor class B, member 1 protein_coding Homo_sapiens

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