C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: scavenger receptor class B, member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086075 Scarb1-001 ENSMUSG00000037936 10090 - 5:125277087-125341094 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086075
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086075 65.684±19.37 1048.744±57.86 31.488±0.57 3.700±0.04 74.840±8.82 20.530±2.38 10.345±4.35 10.477±2.82 53.431±13.74 61.359±10.91 6.303±0.99 346.004±70.03 52.519±33.37 18.016±9.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000399 CIL_000399_0002 CGP 5:125017153-125341094
CIL_00006N CIL_00006N_0003 CGP 5:125277087-125390202

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001530 IEA lipopolysaccharide binding
GO:0001875 IEA lipopolysaccharide receptor activity
GO:0001935 IMP endothelial cell proliferation
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005765 IEA lysosomal membrane
GO:0005886 ISS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005901 IDA caveola
GO:0006702 IEA androgen biosynthetic process
GO:0006707 IMP cholesterol catabolic process
GO:0006869 IEA lipid transport
GO:0006898 IEA receptor-mediated endocytosis
GO:0006910 IEA phagocytosis, recognition
GO:0007155 IEA cell adhesion
GO:0008035 IDA high-density lipoprotein particle binding
GO:0009986 IEA cell surface
GO:0010867 IMP positive regulation of triglyceride biosynthetic process
GO:0010886 ISS positive regulation of cholesterol storage
GO:0010899 IMP regulation of phosphatidylcholine catabolic process
GO:0015914 IMP phospholipid transport
GO:0015920 IEA lipopolysaccharide transport
GO:0016021 IDA integral component of membrane
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 IMP cholesterol transport
GO:0031528 IEA microvillus membrane
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032497 IEA detection of lipopolysaccharide
GO:0033344 IDA cholesterol efflux
GO:0034185 IPI apolipoprotein binding
GO:0034186 IEA apolipoprotein A-I binding
GO:0034375 IMP high-density lipoprotein particle remodeling
GO:0034383 IMP low-density lipoprotein particle clearance
GO:0034384 ISS high-density lipoprotein particle clearance
GO:0042632 IMP cholesterol homeostasis
GO:0042803 IEA protein homodimerization activity
GO:0043534 IMP blood vessel endothelial cell migration
GO:0043654 ISS recognition of apoptotic cell
GO:0043691 IMP reverse cholesterol transport
GO:0044406 IEA adhesion of symbiont to host
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0070328 IMP triglyceride homeostasis
GO:0070506 ISS high-density lipoprotein particle receptor activity
GO:0070508 IDA cholesterol import

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261693 SCARB1-004 protein_coding Homo_sapiens 0 1264
ENST00000339570 SCARB1-001 protein_coding Homo_sapiens 0 1031
ENST00000415380 SCARB1-006 protein_coding Homo_sapiens 0 1031
ENST00000535005 SCARB1-003 processed_transcript Homo_sapiens 0 1088
ENST00000538291 SCARB1-005 retained_intron Homo_sapiens 0 1031
ENST00000544327 SCARB1-009 protein_coding Homo_sapiens 0 941
ENST00000546215 SCARB1-007 protein_coding Homo_sapiens 0 990

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