C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040940 Arhgef1 10090 + 7:24902912-24926592 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047873 Arhgef1-003 24903037-24926589 protein_coding
  ENSMUST00000098683 Arhgef1-001 24903051-24926589 protein_coding
  ENSMUST00000117419 Arhgef1-006 24904407-24926592 protein_coding
  ENSMUST00000117796 Arhgef1-002 24902912-24926592 protein_coding
  ENSMUST00000126484 Arhgef1-013 24923248-24924847 retained_intron
  ENSMUST00000126918 Arhgef1-014 24923353-24925485 retained_intron
  ENSMUST00000127761 Arhgef1-004 24903075-24909960 retained_intron
  ENSMUST00000129383 Arhgef1-009 24903065-24904384 processed_transcript
  ENSMUST00000129928 Arhgef1-012 24919202-24922379 retained_intron
  ENSMUST00000132751 Arhgef1-008 24916831-24926106 protein_coding
  ENSMUST00000132786 Arhgef1-015 24923363-24925936 processed_transcript
  ENSMUST00000144714 Arhgef1-011 24912617-24918392 retained_intron
  ENSMUST00000145783 Arhgef1-005 24904358-24926589 processed_transcript
  ENSMUST00000151121 Arhgef1-010 24907647-24912140 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047873ENSMUST00000098683ENSMUST00000117419ENSMUST00000117796ENSMUST00000129928ENSMUST00000132751ENSMUST00000132786ENSMUST00000144714ENSMUST00000145783
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047873 26.891±5.24 21.318±1.96 19.686±4.36 12.716±0.08 50.481±16.52 11.867±4.86 5.901±1.83 10.796±2.53 11.301±5.11 33.022±2.39 2.517±0.57 24.446±10.62 47.903±40.88 3.224±0.92
ENSMUST00000098683 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.409±0.52 N/A N/A N/A
ENSMUST00000117419 N/A N/A N/A 10.019±0.00 N/A 10.978±2.57 N/A 5.814±0.00 4.718±0.77 N/A 3.743±0.60 18.760±1.94 20.640±11.52 3.438±0.20
ENSMUST00000117796 N/A N/A N/A 10.441±0.00 N/A N/A N/A N/A N/A N/A 3.897±1.70 N/A N/A N/A
ENSMUST00000129928 N/A N/A N/A 29.404±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000132751 N/A N/A N/A 16.636±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000132786 N/A N/A N/A N/A N/A N/A N/A N/A 18.959±0.00 N/A N/A N/A N/A N/A
ENSMUST00000144714 N/A N/A N/A N/A 32.322±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000145783 10.390±0.59 9.515±1.11 7.601±0.00 N/A 48.215±30.65 6.471±0.81 7.219±2.83 8.066±2.55 4.253±1.87 28.860±4.09 3.014±1.95 12.724±3.54 12.605±7.73 2.035±1.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003UK CIL_0003UK_0003 CGP 7:24897381-24926592
CIL_0003VE CIL_0003VE_0002 CGP 7:24902912-24972728

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0044822 IEA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055837 arhgef1b Rho guanine nucleotide exchange factor (GEF) 1b protein_coding Danio_rerio
ENSG00000076928 ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 protein_coding Homo_sapiens

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