C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: Rho guanine nucleotide exchange factor (GEF) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000117419 Arhgef1-006 ENSMUSG00000040940 10090 + 7:24904407-24926592 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000117419
Transcript ID Brain Colon Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000117419 10.019±0.00 10.978±2.57 5.814±0.00 4.718±0.77 3.743±0.60 18.760±1.94 20.640±11.52 3.438±0.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003UK CIL_0003UK_0003 CGP 7:24897381-24926592
CIL_0003VE CIL_0003VE_0002 CGP 7:24902912-24972728

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI protein binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000337665 ARHGEF1-006 protein_coding Homo_sapiens 0 3177
ENST00000347545 ARHGEF1-001 protein_coding Homo_sapiens 0 2780
ENST00000354532 ARHGEF1-005 protein_coding Homo_sapiens 0 3158
ENST00000378152 ARHGEF1-007 protein_coding Homo_sapiens 0 2399
ENST00000594044 ARHGEF1-018 retained_intron Homo_sapiens 0 726
ENST00000594258 ARHGEF1-017 protein_coding Homo_sapiens 0 773
ENST00000595723 ARHGEF1-022 protein_coding Homo_sapiens 0 767
ENST00000595897 ARHGEF1-011 retained_intron Homo_sapiens 0 898
ENST00000598444 ARHGEF1-021 retained_intron Homo_sapiens 3e-29 132
ENST00000598812 ARHGEF1-014 nonsense_mediated_decay Homo_sapiens 0 281
ENST00000599589 ARHGEF1-009 protein_coding Homo_sapiens 0 1700
ENST00000599846 ARHGEF1-010 protein_coding Homo_sapiens 0 2080
ENST00000600274 ARHGEF1-002 retained_intron Homo_sapiens 0 2780
ENST00000600387 ARHGEF1-012 retained_intron Homo_sapiens 0 267
ENST00000600517 ARHGEF1-019 nonsense_mediated_decay Homo_sapiens 0 287

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