C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041540 Sox5 10090 - 6:143828425-144781977 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038815 Sox5-001 143828425-144209480 protein_coding
  ENSMUST00000077160 Sox5-002 143828425-144209452 protein_coding
  ENSMUST00000111746 Sox5-004 143839443-143947101 processed_transcript
  ENSMUST00000111748 Sox5-003 143828425-143947106 protein_coding
  ENSMUST00000111749 Sox5-005 143828425-144209558 protein_coding
  ENSMUST00000124233 Sox5-010 143841275-143947088 protein_coding
  ENSMUST00000129050 Sox5-007 143906572-144204427 retained_intron
  ENSMUST00000139478 Sox5-012 144116478-144204057 processed_transcript
  ENSMUST00000141102 Sox5-009 143843739-144781977 retained_intron
  ENSMUST00000142294 Sox5-006 144021142-144209480 retained_intron
  ENSMUST00000144289 Sox5-013 143844815-143947097 protein_coding
  ENSMUST00000149451 Sox5-008 144104452-144781919 processed_transcript
  ENSMUST00000150087 Sox5-011 144154829-144209568 retained_intron
  ENSMUST00000170367 Sox5-201 143828425-144209568 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038815ENSMUST00000077160ENSMUST00000111748ENSMUST00000111749ENSMUST00000124233ENSMUST00000139478ENSMUST00000141102ENSMUST00000144289
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038815 N/A 0.354±0.00 3.571±2.44 0.273±0.17 N/A N/A N/A 0.461±0.22 N/A N/A N/A 0.238±0.16 N/A
ENSMUST00000077160 N/A N/A 0.558±0.00 0.203±0.00 N/A 0.098±0.03 N/A N/A N/A N/A 0.762±0.00 0.073±0.00 N/A
ENSMUST00000111748 0.877±0.05 N/A N/A 0.529±0.00 0.203±0.07 N/A 0.386±0.26 N/A 1.617±0.00 0.076±0.02 2.480±1.01 0.247±0.00 6.947±1.39
ENSMUST00000111749 0.509±0.00 0.900±0.20 4.518±0.18 N/A 0.153±0.00 0.199±0.04 0.220±0.00 0.435±0.21 N/A 0.019±0.00 N/A 0.590±0.04 N/A
ENSMUST00000124233 N/A N/A 10.133±0.00 N/A N/A N/A N/A N/A N/A 0.203±0.00 8.212±0.00 0.972±0.00 56.394±47.74
ENSMUST00000139478 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.480±0.00 N/A N/A N/A
ENSMUST00000141102 N/A 0.580±0.00 N/A 0.365±0.00 N/A N/A 0.293±0.02 0.846±0.00 0.934±0.27 0.033±0.01 2.990±0.00 0.340±0.19 N/A
ENSMUST00000144289 2.221±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 63.765±15.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Y0 CIL_0006Y0_0003 CGP 6:143167230-144781977
CIL_0007NR CIL_0007NR_0002 UCNEbase 6:143260703-144754208
CIL_0004XB CIL_0004XB_0002 CGP 6:143828425-145076184

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001701 IMP in utero embryonic development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0021953 IGI central nervous system neuron differentiation
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045165 IGI cell fate commitment
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity
GO:0048709 IMP oligodendrocyte differentiation
GO:0051216 IGI cartilage development
GO:0060164 IMP regulation of timing of neuron differentiation
GO:0061036 IEA positive regulation of cartilage development
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:2000741 IEA positive regulation of mesenchymal stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011582 sox5 SRY-box containing gene 5 protein_coding Danio_rerio
ENSG00000134532 SOX5 SRY (sex determining region Y)-box 5 protein_coding Homo_sapiens

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