C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine hydroxymethyltransferase 1 (soluble)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000316694 SHMT1-001 ENSG00000176974 9606 - 17:18327873-18363487 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316694
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316694 19.998±0.00 6.290±0.00 3.703±0.00 11.084±9.44 3.209±1.96 2.030±1.54 57.918±46.52 66.150±65.30 5.102±0.00 5.777±0.00 6.890±2.18 6.543±1.96 8.815±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058O CIL_00058O_0002 CGP 17:18315310-18363563

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004372 IDA:IEA glycine hydroxymethyltransferase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IDA cytosol
GO:0006544 IEA glycine metabolic process
GO:0006545 IEA glycine biosynthetic process
GO:0006563 IEA L-serine metabolic process
GO:0006565 IDA L-serine catabolic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0008732 IEA L-allo-threonine aldolase activity
GO:0009058 IEA biosynthetic process
GO:0009113 IDA purine nucleobase biosynthetic process
GO:0016597 IEA amino acid binding
GO:0019264 IEA glycine biosynthetic process from serine
GO:0030170 IEA:IDA pyridoxal phosphate binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0035999 IEA tetrahydrofolate interconversion
GO:0042802 IEA identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0045329 TAS carnitine biosynthetic process
GO:0046655 IDA folic acid metabolic process
GO:0051262 IDA protein tetramerization
GO:0051289 IEA protein homotetramerization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018744 Shmt1-001 protein_coding Mus_musculus 0 1483
ENSMUST00000174214 Shmt1-010 protein_coding Mus_musculus 0 1271
ENSMUST00000174174 Shmt1-007 nonsense_mediated_decay Mus_musculus 0 1153
ENSMUST00000174093 Shmt1-005 processed_transcript Mus_musculus 0 950
ENSMUST00000174719 Shmt1-006 protein_coding Mus_musculus 0 905
ENSMUST00000173260 Shmt1-004 retained_intron Mus_musculus 0 904
ENSDART00000074737 shmt1-001 protein_coding Danio_rerio 0 582
ENSMUST00000172804 Shmt1-011 retained_intron Mus_musculus 0 562
ENSMUST00000124227 Shmt1-003 retained_intron Mus_musculus 0 488
ENSDART00000141578 shmt1-003 protein_coding Danio_rerio 0 396
ENSDART00000132225 shmt1-002 protein_coding Danio_rerio 0 379
ENSMUST00000173698 Shmt1-008 processed_transcript Mus_musculus 0 327

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