C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: topoisomerase (DNA) III alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000002891 Top3a-002 ENSMUSG00000002814 10090 - 11:60740058-60777365 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002891
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002891 2.049±0.26 1.505±0.63 3.138±0.10 2.831±1.67 2.848±0.35 2.924±0.62 0.707±0.30 1.946±0.45 2.566±1.45 2.709±0.26 0.732±0.27 3.369±1.38 4.031±0.97 6.488±1.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005K3 CIL_0005K3_0002 CGP 11:60728398-60777365
CIL_00002B CIL_00002B_0003 CGP 11:60740058-60788287

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003917 ISS DNA topoisomerase type I activity
GO:0005515 IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005694 IEA chromosome
GO:0006265 ISS DNA topological change
GO:0008270 IEA zinc ion binding
GO:0016605 IEA PML body

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000321105 TOP3A-001 protein_coding Homo_sapiens 0 3109
ENST00000461127 TOP3A-004 nonsense_mediated_decay Homo_sapiens 0 353
ENST00000469739 TOP3A-003 retained_intron Homo_sapiens 0 1253
ENST00000472959 TOP3A-005 retained_intron Homo_sapiens 3e-23 113
ENST00000477508 TOP3A-006 retained_intron Homo_sapiens 0 329
ENST00000542570 TOP3A-201 protein_coding Homo_sapiens 0 3109
ENST00000580095 TOP3A-020 protein_coding Homo_sapiens 0 3049
ENST00000581536 TOP3A-012 nonsense_mediated_decay Homo_sapiens 0 486
ENST00000582981 TOP3A-009 nonsense_mediated_decay Homo_sapiens 0 2752
ENST00000583328 TOP3A-018 retained_intron Homo_sapiens 0 453
ENST00000583804 TOP3A-013 retained_intron Homo_sapiens 0 1273
ENST00000584582 TOP3A-010 nonsense_mediated_decay Homo_sapiens 0 2752
ENST00000584669 TOP3A-011 processed_transcript Homo_sapiens 0 473

Loading