C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: topoisomerase (DNA) III alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000321105 TOP3A-001 ENSG00000177302 9606 - 17:18273967-18314993 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonHeartLiverMuscleOvaryPlacentaENST00000321105
Transcript ID Breast Colon Heart Liver Muscle Ovary Placenta
ENST00000321105 0.999±0.00 1.129±0.00 0.400±0.28 1.157±0.14 1.111±0.00 1.385±0.34 2.300±1.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005K3 CIL_0005K3_0001 CGP 17:18260534-18315007
CIL_00002B CIL_00002B_0002 CGP 17:18271428-18323203

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003916 IEA DNA topoisomerase activity
GO:0003917 IDA DNA topoisomerase type I activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005694 IEA chromosome
GO:0006265 IDA:IEA DNA topological change
GO:0007126 TAS meiotic nuclear division
GO:0008270 IEA zinc ion binding
GO:0016605 IDA PML body

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002891 Top3a-002 protein_coding Mus_musculus 0 3109
ENSMUST00000102668 Top3a-003 protein_coding Mus_musculus 0 2996
ENSMUST00000117743 Top3a-001 protein_coding Mus_musculus 0 2608
ENSMUST00000120417 Top3a-006 protein_coding Mus_musculus 0 2414
ENSMUST00000124799 Top3a-005 retained_intron Mus_musculus 0 466
ENSMUST00000130068 Top3a-004 protein_coding Mus_musculus 0 219

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