C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polymerase (DNA directed), alpha 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000006856 Pola1-001 ENSMUSG00000006678 10090 - X:93304767-93632155 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006856
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006856 0.504±0.24 0.304±0.08 1.048±0.12 1.180±0.50 0.262±0.10 0.462±0.13 0.256±0.14 0.307±0.05 2.317±2.64 0.436±0.04 0.142±0.04 1.354±1.41 2.278±1.80 0.236±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PA CIL_0007PA_0002 UCNEbase X:92514784-93497939
CIL_0009CI CIL_0009CI_0002 VISTA X:92999508-93601047
CIL_0008W6 CIL_0008W6_0002 VISTA X:93001146-93602798
CIL_0008W7 CIL_0008W7_0002 VISTA X:93009764-93611448
CIL_0008W8 CIL_0008W8_0002 VISTA X:93076664-93678616
CIL_0008NM CIL_0008NM_0002 VISTA X:93107742-93710584
CIL_0008NL CIL_0008NL_0002 VISTA X:93128674-93730367
CIL_0008NF CIL_0008NF_0002 VISTA X:93157367-93758875
CIL_0008NE CIL_0008NE_0002 VISTA X:93196691-93798662
CIL_00084H CIL_00084H_0002 VISTA X:93277817-93878339

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 ISS nucleotide binding
GO:0000785 ISS chromatin
GO:0001882 IEA nucleoside binding
GO:0003677 ISS DNA binding
GO:0003682 ISS chromatin binding
GO:0003887 ISS DNA-directed DNA polymerase activity
GO:0003896 ISS DNA primase activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005635 ISS nuclear envelope
GO:0005654 ISS nucleoplasm
GO:0005658 ISS alpha DNA polymerase:primase complex
GO:0005730 ISS nucleolus
GO:0005737 IEA cytoplasm
GO:0006260 ISS DNA replication
GO:0006269 IEA DNA replication, synthesis of RNA primer
GO:0006270 ISS DNA replication initiation
GO:0006271 ISS DNA strand elongation involved in DNA replication
GO:0006272 ISS leading strand elongation
GO:0006273 ISS lagging strand elongation
GO:0006303 ISS double-strand break repair via nonhomologous end joining
GO:0008283 ISS cell proliferation
GO:0008408 IBA 3'-5' exonuclease activity
GO:0016363 ISS nuclear matrix
GO:0019901 IEA protein kinase binding
GO:0019985 IBA translesion synthesis
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0090305 IBA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000379059 POLA1-001 protein_coding Homo_sapiens 0 5428
ENST00000379068 POLA1-005 protein_coding Homo_sapiens 0 5478
ENST00000480125 POLA1-002 processed_transcript Homo_sapiens 0 477
ENST00000493342 POLA1-003 processed_transcript Homo_sapiens 0 588
ENST00000494204 POLA1-004 processed_transcript Homo_sapiens 0 865
ENST00000611764 POLA1-201 protein_coding Homo_sapiens 0 5415

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