C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000027056 Prex2-001 ENSMUSG00000048960 10090 + 1:10993465-11303681 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027056
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027056 4.083±1.18 0.912±0.39 3.547±0.28 1.001±0.68 2.085±0.26 0.839±0.21 2.089±0.62 1.742±0.48 0.372±0.12 23.845±1.81 0.259±0.06 0.835±0.28 2.331±1.14 0.079±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005BU CIL_0005BU_0003 CGP 1:10324720-11303681
CIL_00087Z CIL_00087Z_0002 VISTA 1:10726040-11328544
CIL_0001SD CIL_0001SD_0003 CGP 1:10993465-11975901

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005886 IDA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0008344 IMP adult locomotory behavior
GO:0014065 IMP phosphatidylinositol 3-kinase signaling
GO:0030675 IEA Rac GTPase activator activity
GO:0030676 IEA Rac guanyl-nucleotide exchange factor activity
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0048813 IMP dendrite morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000250559 RAP1B-001 protein_coding Homo_sapiens 0.0009 53
ENST00000288368 PREX2-001 protein_coding Homo_sapiens 0 5384
ENST00000304987 SIK2-001 protein_coding Homo_sapiens 0.00005 57
ENST00000326303 ACOT4-001 protein_coding Homo_sapiens 0.0002 53
ENST00000407780 ICOSLG-001 protein_coding Homo_sapiens 0.0001 55
ENST00000431918 CLDN4-001 protein_coding Homo_sapiens 0.0003 53
ENST00000435050 CLDN4-002 protein_coding Homo_sapiens 0.0003 53
ENST00000460807 NKTR-013 retained_intron Homo_sapiens 0.00006 53
ENST00000476494 CLDN4-004 processed_transcript Homo_sapiens 0.00004 53
ENST00000478757 RP11-2I17.1-001 processed_pseudogene Homo_sapiens 0.000001 58
ENST00000491209 BTNL9-003 nonsense_mediated_decay Homo_sapiens 0.0001 53
ENST00000508351 NKTR-018 retained_intron Homo_sapiens 0.00006 53
ENST00000512570 BTNL9-012 retained_intron Homo_sapiens 0.00006 53
ENST00000517617 PREX2-003 processed_transcript Homo_sapiens 0 3240
ENST00000520235 PREX2-004 processed_transcript Homo_sapiens 0 418
ENST00000522247 PREX2-005 processed_transcript Homo_sapiens 0 368
ENST00000526067 ARHGEF12-014 retained_intron Homo_sapiens 0.00002 55
ENST00000526829 VPS11-007 retained_intron Homo_sapiens 0.0001 53
ENST00000529398 PREX2-002 processed_transcript Homo_sapiens 0 3085
ENST00000599628 TRPM4-002 protein_coding Homo_sapiens 0.00003 55

Loading