C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: Rap guanine nucleotide exchange factor (GEF) 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028525 Rapgef4-005 ENSMUSG00000049044 10090 + 2:72054604-72257472 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENSMUST00000028525
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENSMUST00000028525 0.730±0.16 24.666±10.92 1.183±0.46 0.824±0.17 0.477±0.13 1.104±0.19 2.248±0.15 3.649±0.72 0.088±0.03 3.088±1.99 0.701±0.64 0.465±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004KA CIL_0004KA_0002 CGP 2:71873224-72257474
CIL_0003IJ CIL_0003IJ_0003 CGP 2:71981240-72442610

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0005952 IEA cAMP-dependent protein kinase complex
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008603 IEA cAMP-dependent protein kinase regulator activity
GO:0017156 IDA calcium ion-dependent exocytosis
GO:0017157 IDA regulation of exocytosis
GO:0019933 IDA cAMP-mediated signaling
GO:0030073 IDA insulin secretion
GO:0043547 IEA positive regulation of GTPase activity
GO:0045859 IEA regulation of protein kinase activity
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000397081 RAPGEF4-001 protein_coding Homo_sapiens 0 3740
ENST00000397085 RAPGEF4-003 protein_coding Homo_sapiens 0 760
ENST00000397087 RAPGEF4-004 protein_coding Homo_sapiens 0 3766
ENST00000409036 RAPGEF4-011 protein_coding Homo_sapiens 0 3042
ENST00000459852 RAPGEF4-008 processed_transcript Homo_sapiens 0 625
ENST00000466030 RAPGEF4-006 processed_transcript Homo_sapiens 0 610
ENST00000473003 RAPGEF4-013 processed_transcript Homo_sapiens 0 501
ENST00000473043 RAPGEF4-010 processed_transcript Homo_sapiens 0 1295
ENST00000473182 RAPGEF4-007 retained_intron Homo_sapiens 0 248
ENST00000484645 RAPGEF4-002 retained_intron Homo_sapiens 0 409
ENST00000535187 RAPGEF4-201 protein_coding Homo_sapiens 0 3504
ENST00000538974 RAPGEF4-202 protein_coding Homo_sapiens 0 3502
ENST00000540783 RAPGEF4-203 protein_coding Homo_sapiens 0 3735

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