C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methyl-CpG binding domain protein 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000032469 Mbd4-001 ENSMUSG00000030322 10090 - 6:115840697-115853371 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032469
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032469 0.301±0.06 0.198±0.13 0.583±0.08 1.388±0.19 0.377±0.05 0.374±0.13 0.200±0.12 0.278±0.07 1.017±0.86 0.463±0.14 0.214±0.08 0.719±0.35 1.057±0.55 1.584±0.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00030X CIL_00030X_0002 CGP 6:115810729-115853371
CIL_00030Y CIL_00030Y_0002 CGP 6:115840697-115926699

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000785 IDA chromatin
GO:0003677 IDA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006284 IEA base-excision repair
GO:0006306 TAS DNA methylation
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007095 IMP mitotic G2 DNA damage checkpoint
GO:0008263 IEA pyrimidine-specific mismatch base pair DNA N-glycosylase activity
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009314 IMP response to radiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000249910 MBD4-001 protein_coding Homo_sapiens 0 747
ENST00000393278 MBD4-201 protein_coding Homo_sapiens 0 704
ENST00000429544 MBD4-003 protein_coding Homo_sapiens 0 706
ENST00000503197 MBD4-002 protein_coding Homo_sapiens 0 551
ENST00000507208 MBD4-009 protein_coding Homo_sapiens 0 628
ENST00000509587 MBD4-004 processed_transcript Homo_sapiens 0 270
ENST00000509828 MBD4-005 nonsense_mediated_decay Homo_sapiens 0 431
ENST00000515266 MBD4-007 retained_intron Homo_sapiens 0 387

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