C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear factor I/B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000050872 Nfib-201 ENSMUSG00000008575 10090 - 4:82290173-82505308 protein_coding

Mus musculus EnsemblGRCm38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000050872
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000050872 4.890±1.65 3.903±1.13 1.975±0.45 7.048±1.28 3.093±0.42 2.597±0.61 2.273±0.44 2.282±2.04 8.668±1.01 2.321±0.67 0.367±0.16 0.207±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000746 CIL_000746_0002 CGP 4:81278500-82705750
CIL_0007VJ CIL_0007VJ_0002 VISTA 4:81853582-82454380
CIL_000143 CIL_000143_0002 CGP 4:82290173-82859958

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 ISS sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001106 IEA RNA polymerase II transcription corepressor activity
GO:0002062 IMP chondrocyte differentiation
GO:0003677 ISS DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0006260 IEA DNA replication
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0008285 IMP negative regulation of cell proliferation
GO:0010001 IMP glial cell differentiation
GO:0021740 IMP principal sensory nucleus of trigeminal nerve development
GO:0021960 IMP anterior commissure morphogenesis
GO:0030324 IMP lung development
GO:0030900 IMP forebrain development
GO:0030902 IMP hindbrain development
GO:0043392 IEA negative regulation of DNA binding
GO:0044300 IDA cerebellar mossy fiber
GO:0045944 IDA:IMP positive regulation of transcription from RNA polymerase II promoter
GO:0060486 IMP Clara cell differentiation
GO:0060509 IMP Type I pneumocyte differentiation
GO:0060510 IMP Type II pneumocyte differentiation
GO:0061141 IMP lung ciliated cell differentiation
GO:0071679 IMP commissural neuron axon guidance
GO:2000791 IMP negative regulation of mesenchymal cell proliferation involved in lung development
GO:2000795 IMP negative regulation of epithelial cell proliferation involved in lung morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000380921 NFIB-006 protein_coding Homo_sapiens 0 1430
ENST00000380924 NFIB-008 protein_coding Homo_sapiens 0 1005
ENST00000380934 NFIB-201 protein_coding Homo_sapiens 0 3997
ENST00000380953 NFIB-005 protein_coding Homo_sapiens 0 2374
ENST00000380959 NFIB-001 protein_coding Homo_sapiens 0 3997
ENST00000397575 NFIB-004 protein_coding Homo_sapiens 0 3819
ENST00000397579 NFIB-002 protein_coding Homo_sapiens 0 2475
ENST00000397581 NFIB-003 protein_coding Homo_sapiens 0 3975
ENST00000493697 NFIB-007 protein_coding Homo_sapiens 0 730
ENST00000543693 NFIB-202 protein_coding Homo_sapiens 0 4355
ENST00000606230 NFIB-009 protein_coding Homo_sapiens 0 241
ENST00000622101 NFIB-203 protein_coding Homo_sapiens 0 5801
ENST00000622520 NFIB-204 protein_coding Homo_sapiens 0 1434

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