C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000053880 Grin2b-001 ENSMUSG00000030209 10090 - 6:135713232-136171722 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000053880
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000053880 0.047±0.02 0.010±0.00 0.001±0.00 5.354±3.71 0.012±0.01 0.026±0.01 0.005±0.00 0.002±0.00 0.004±0.00 0.014±0.01 0.002±0.00 0.197±0.07 0.002±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003H7 CIL_0003H7_0002 CGP 6:135362931-136173511

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 IMP behavioral fear response
GO:0001701 IMP in utero embryonic development
GO:0001964 IMP startle response
GO:0001967 IMP suckling behavior
GO:0004972 IMP N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005261 IGI cation channel activity
GO:0005262 IMP calcium channel activity
GO:0005515 IPI protein binding
GO:0006812 IGI cation transport
GO:0006816 IMP calcium ion transport
GO:0007268 IMP synaptic transmission
GO:0007423 IMP sensory organ development
GO:0007612 IDA learning
GO:0007613 IDA memory
GO:0008021 IDA synaptic vesicle
GO:0010738 IMP regulation of protein kinase A signaling
GO:0014069 IDA postsynaptic density
GO:0016020 IDA membrane
GO:0016594 IEA glycine binding
GO:0017146 IPI N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0034220 IBA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042596 IMP fear response
GO:0045202 IDA synapse
GO:0045211 IDA postsynaptic membrane
GO:0045471 IMP response to ethanol
GO:0048167 IMP regulation of synaptic plasticity
GO:0048266 IMP behavioral response to pain
GO:0050966 IMP detection of mechanical stimulus involved in sensory perception of pain
GO:0060078 IMP regulation of postsynaptic membrane potential
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0070588 IMP calcium ion transmembrane transport
GO:0097481 IDA neuronal postsynaptic density
GO:0098655 IGI cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330684 GRIN2A-002 protein_coding Homo_sapiens 0 869
ENST00000396573 GRIN2A-001 protein_coding Homo_sapiens 0 869
ENST00000396575 GRIN2A-201 protein_coding Homo_sapiens 0 869
ENST00000463531 GRIN2A-003 processed_transcript Homo_sapiens 0 231
ENST00000535259 GRIN2A-202 protein_coding Homo_sapiens 0 869
ENST00000562109 GRIN2A-006 protein_coding Homo_sapiens 0 869
ENST00000609686 GRIN2B-001 protein_coding Homo_sapiens 0 6545

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