C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: signal transducer and activator of transcription 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000070968 Stat1-001 ENSMUSG00000026104 10090 + 1:52119455-52161865 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonOvaryENSMUST00000070968
Transcript ID Adrenal Brain Colon Ovary
ENSMUST00000070968 6.087±0.02 0.315±0.00 1.453±0.11 4.014±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AM CIL_0009AM_0002 VISTA 1:51779533-52380137
CIL_0002AL CIL_0002AL_0002 CGP 1:51987148-52161865
CIL_0002SJ CIL_0002SJ_0003 CGP 1:52119440-52233232

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IEA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000983 IEA RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0003677 IEA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0006351 IMP transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007259 IEA JAK-STAT cascade
GO:0007584 IEA response to nutrient
GO:0008015 IEA blood circulation
GO:0008284 IEA positive regulation of cell proliferation
GO:0009612 IEA response to mechanical stimulus
GO:0009617 IDA response to bacterium
GO:0014070 IEA response to organic cyclic compound
GO:0016525 IEA negative regulation of angiogenesis
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019899 IEA enzyme binding
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0031730 IEA CCR5 chemokine receptor binding
GO:0032496 IDA response to lipopolysaccharide
GO:0032869 IEA cellular response to insulin stimulus
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0034097 IEA response to cytokine
GO:0034240 IMP negative regulation of macrophage fusion
GO:0035458 IEA cellular response to interferon-beta
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 IDA response to exogenous dsRNA
GO:0043434 IEA response to peptide hormone
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051591 IEA response to cAMP
GO:0061326 IEA renal tubule development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264657 STAT3-001 protein_coding Homo_sapiens 4e-28 132
ENST00000361099 STAT1-001 protein_coding Homo_sapiens 0 2627
ENST00000389272 STAT3-013 protein_coding Homo_sapiens 2e-28 132
ENST00000392322 STAT1-003 protein_coding Homo_sapiens 0 2359
ENST00000392323 STAT1-002 protein_coding Homo_sapiens 0 2357
ENST00000404395 STAT3-002 protein_coding Homo_sapiens 2e-28 132
ENST00000409465 STAT1-011 protein_coding Homo_sapiens 0 2627
ENST00000415035 STAT1-010 nonsense_mediated_decay Homo_sapiens 0 261
ENST00000423282 STAT1-005 nonsense_mediated_decay Homo_sapiens 0 211
ENST00000452281 STAT1-006 nonsense_mediated_decay Homo_sapiens 0 1637
ENST00000464072 STAT1-009 retained_intron Homo_sapiens 0 549
ENST00000540176 STAT1-201 protein_coding Homo_sapiens 0 1905
ENST00000585517 STAT3-012 protein_coding Homo_sapiens 3e-28 132
ENST00000588969 STAT3-011 protein_coding Homo_sapiens 2e-28 132

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