C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: thymine DNA glycosylase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000092266 Tdg-001 ENSMUSG00000034674 10090 + 10:82629828-82650324 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000092266
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000092266 2.558±0.65 9.268±0.80 20.136±12.05 4.022±1.06 2.876±1.18 2.399±0.42 2.849±0.79 6.097±5.12 3.112±0.66 4.267±0.96 4.742±2.45 11.327±3.76 1.404±0.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000002 CIL_000002_0003 CGP 10:82619851-82650799
CIL_0002S6 CIL_0002S6_0002 CGP 10:82629828-82690650

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001104 IGI RNA polymerase II transcription cofactor activity
GO:0003690 ISS double-stranded DNA binding
GO:0005080 IPI protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006284 IDA base-excision repair
GO:0006298 ISS mismatch repair
GO:0006366 IGI transcription from RNA polymerase II promoter
GO:0009790 IMP embryo development
GO:0016568 IEA chromatin modification
GO:0016605 IDA PML body
GO:0019104 IDA DNA N-glycosylase activity
GO:0030983 ISS mismatched DNA binding
GO:0032091 IDA negative regulation of protein binding
GO:0032183 IPI SUMO binding
GO:0035562 IDA negative regulation of chromatin binding
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0042803 ISS protein homodimerization activity
GO:0043566 IDA structure-specific DNA binding
GO:0080111 IMP DNA demethylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000266775 TDG-003 protein_coding Homo_sapiens 0 1085
ENST00000392872 TDG-001 protein_coding Homo_sapiens 0 1317
ENST00000537100 TDG-008 protein_coding Homo_sapiens 0 579
ENST00000540956 TDG-006 nonsense_mediated_decay Homo_sapiens 0 575
ENST00000542926 TDG-009 retained_intron Homo_sapiens 0 488
ENST00000543961 TDGP1-001 processed_pseudogene Homo_sapiens 0 968
ENST00000544861 TDG-004 protein_coding Homo_sapiens 0 1077

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