C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: thymine-DNA glycosylase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392872 TDG-001 ENSG00000139372 9606 + 12:103965804-103988874 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392872
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392872 0.436±0.00 1.156±0.02 1.064±0.62 1.116±0.41 1.149±0.49 4.279±0.00 1.269±0.51 1.498±0.50 0.597±0.00 8.460±4.10 5.925±1.80 1.997±1.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000002 CIL_000002_0002 CGP 12:103950202-103988874
CIL_0002S6 CIL_0002S6_0001 CGP 12:103965804-104064183

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001104 IEA RNA polymerase II transcription cofactor activity
GO:0003684 TAS damaged DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005886 IDA plasma membrane
GO:0006281 IEA:TAS DNA repair
GO:0006284 IDA base-excision repair
GO:0006285 TAS base-excision repair, AP site formation
GO:0006298 IEA:IDA mismatch repair
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0008134 IEA transcription factor binding
GO:0008263 IDA pyrimidine-specific mismatch base pair DNA N-glycosylase activity
GO:0009790 ISS embryo development
GO:0016568 IEA chromatin modification
GO:0016605 IEA PML body
GO:0016798 IEA hydrolase activity, acting on glycosyl bonds
GO:0019104 IDA DNA N-glycosylase activity
GO:0019904 IEA protein domain specific binding
GO:0030983 IEA:IDA mismatched DNA binding
GO:0032091 IEA negative regulation of protein binding
GO:0032183 IEA SUMO binding
GO:0035562 IEA negative regulation of chromatin binding
GO:0040029 ISS regulation of gene expression, epigenetic
GO:0042803 IDA protein homodimerization activity
GO:0043566 ISS structure-specific DNA binding
GO:0045008 TAS depyrimidination
GO:0080111 ISS DNA demethylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000151390 Tdg-002 protein_coding Mus_musculus 0 1317
ENSMUST00000092266 Tdg-001 protein_coding Mus_musculus 0 1317
ENSMUST00000051363 Gm5806-201 processed_pseudogene Mus_musculus 0 1301
ENSMUST00000121229 Gm9855-001 processed_pseudogene Mus_musculus 0 1029
ENSMUST00000182353 Gm5597-001 processed_pseudogene Mus_musculus 0 1013
ENSMUST00000176326 Tdg-009 protein_coding Mus_musculus 0 856
ENSMUST00000176195 Tdg-010 nonsense_mediated_decay Mus_musculus 0 590
ENSMUST00000177353 Tdg-011 protein_coding Mus_musculus 0 571
ENSMUST00000125970 Tdg-007 retained_intron Mus_musculus 0 429
ENSMUST00000142658 Tdg-008 retained_intron Mus_musculus 0 313
ENSMUST00000135652 Tdg-006 retained_intron Mus_musculus 0 303

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