C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: src homology 2 domain-containing transforming protein C1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000094378 Shc1-002 ENSMUSG00000042626 10090 + 3:89421628-89429099 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungOvaryPlacentaENSMUST00000094378
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Ovary Placenta
ENSMUST00000094378 26.460±12.42 14.608±3.12 10.937±0.33 1.867±0.15 16.024±3.24 10.513±2.42 2.536±0.55 4.421±1.11 8.477±2.22 25.607±1.61 9.744±2.25

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 ISS MAPK cascade
GO:0000187 IMP:ISS activation of MAPK activity
GO:0001525 IMP angiogenesis
GO:0005158 IEA insulin receptor binding
GO:0005159 IEA insulin-like growth factor receptor binding
GO:0005168 IEA neurotrophin TRKA receptor binding
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0007173 IDA epidermal growth factor receptor signaling pathway
GO:0007507 IMP heart development
GO:0016337 IMP single organismal cell-cell adhesion
GO:0030971 IEA:IPI receptor tyrosine kinase binding
GO:0031532 IMP actin cytoskeleton reorganization
GO:0040008 IEA regulation of growth
GO:0042127 IMP regulation of cell proliferation
GO:0046875 IPI ephrin receptor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000366442 SHC1-009 protein_coding Homo_sapiens 0 619
ENST00000368445 SHC1-001 protein_coding Homo_sapiens 0 2495
ENST00000368449 SHC1-003 protein_coding Homo_sapiens 0 1437
ENST00000368450 SHC1-007 protein_coding Homo_sapiens 0 1925
ENST00000368453 SHC1-006 protein_coding Homo_sapiens 0 1916
ENST00000412170 SHC1-008 protein_coding Homo_sapiens 0 628
ENST00000414115 SHC1-004 protein_coding Homo_sapiens 0 568
ENST00000425230 SHC1P1-001 processed_pseudogene Homo_sapiens 0 1759
ENST00000444179 SHC1-005 protein_coding Homo_sapiens 0 717
ENST00000444664 SHC1-010 protein_coding Homo_sapiens 0 207
ENST00000448116 SHC1-002 protein_coding Homo_sapiens 0 2488
ENST00000490667 SHC1-011 processed_transcript Homo_sapiens 0 303
ENST00000589195 SHC1P2-001 processed_pseudogene Homo_sapiens 0 767

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