C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: arrestin, beta 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102563 Arrb2-001 ENSMUSG00000060216 10090 + 11:70432698-70440823 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000102563
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000102563 3.003±0.00 1.861±0.59 4.144±0.19 8.634±2.85 1.599±0.24 1.256±0.20 1.764±0.78 3.016±1.68 4.413±0.47 2.622±0.71 1.009±0.00 0.955±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PS CIL_0001PS_0002 CGP 11:70392883-70440828
CIL_000106 CIL_000106_0002 CGP 11:70432635-70453727

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001932 IDA regulation of protein phosphorylation
GO:0002092 ISS positive regulation of receptor internalization
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005737 ISS cytoplasm
GO:0005905 IEA coated pit
GO:0007628 IMP adult walking behavior
GO:0008277 IMP regulation of G-protein coupled receptor protein signaling pathway
GO:0015031 IEA protein transport
GO:0030139 ISS endocytic vesicle
GO:0032226 IMP positive regulation of synaptic transmission, dopaminergic
GO:0032691 IMP negative regulation of interleukin-1 beta production
GO:0032695 IMP negative regulation of interleukin-12 production
GO:0032715 IMP negative regulation of interleukin-6 production
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0034122 IMP negative regulation of toll-like receptor signaling pathway
GO:0043422 IPI protein kinase B binding
GO:0051897 IMP positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000269260 ARRB2-002 protein_coding Homo_sapiens 0 1615
ENST00000346341 ARRB2-001 protein_coding Homo_sapiens 0 1162
ENST00000381488 ARRB2-009 protein_coding Homo_sapiens 0 1339
ENST00000412477 ARRB2-006 protein_coding Homo_sapiens 0 1074
ENST00000570718 ARRB2-012 processed_transcript Homo_sapiens 0 351
ENST00000570739 ARRB2-011 processed_transcript Homo_sapiens 3e-20 102
ENST00000571206 ARRB2-008 protein_coding Homo_sapiens 0 1502
ENST00000571428 ARRB2-020 protein_coding Homo_sapiens 0 929
ENST00000571791 ARRB2-014 retained_intron Homo_sapiens 0 547
ENST00000572457 ARRB2-003 protein_coding Homo_sapiens 0 1404
ENST00000572497 ARRB2-016 nonsense_mediated_decay Homo_sapiens 0 324
ENST00000572782 ARRB2-015 retained_intron Homo_sapiens 2e-22 110
ENST00000573886 ARRB2-018 retained_intron Homo_sapiens 0 303
ENST00000574502 ARRB2-010 nonsense_mediated_decay Homo_sapiens 0 303
ENST00000574888 ARRB2-013 retained_intron Homo_sapiens 0 279
ENST00000574954 ARRB2-004 protein_coding Homo_sapiens 0 1502
ENST00000575131 ARRB2-017 retained_intron Homo_sapiens 0 505
ENST00000575877 ARRB2-007 protein_coding Homo_sapiens 0 1068
ENST00000576235 ARRB2-021 nonsense_mediated_decay Homo_sapiens 0 732
ENST00000577054 ARRB2-019 retained_intron Homo_sapiens 0 233

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