C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tryptophan hydroxylase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107669 Tph1-001 ENSMUSG00000040046 10090 - 7:46647130-46667377 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverMuscleOvaryPlacentaENSMUST00000107669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Muscle Ovary Placenta
ENSMUST00000107669 0.046±0.03 0.058±0.00 0.009±0.00 0.096±0.01 0.398±0.27 2.684±0.77 0.019±0.00 0.016±0.00 0.414±0.19 0.077±0.04 0.528±0.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IE CIL_0001IE_0003 CGP 7:46443168-46672537
CIL_00041A CIL_00041A_0003 CGP 7:46647130-46710680

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004510 IDA tryptophan 5-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0009072 IEA aromatic amino acid family metabolic process
GO:0016597 IEA amino acid binding
GO:0042427 IEA serotonin biosynthetic process
GO:0045600 IMP positive regulation of fat cell differentiation
GO:0046849 IGI bone remodeling
GO:0055114 IEA oxidation-reduction process
GO:0060749 IMP mammary gland alveolus development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000250018 TPH1-001 protein_coding Homo_sapiens 0 1410
ENST00000417164 TPH1-002 nonsense_mediated_decay Homo_sapiens 0 771
ENST00000525406 TPH1-003 processed_transcript Homo_sapiens 0 252
ENST00000528338 TPH1-004 protein_coding Homo_sapiens 0 414

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