C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: tryptophan hydroxylase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000250018 TPH1-001 ENSG00000129167 9606 - 11:18017564-18041325 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonLungOvaryTestisENST00000250018
Transcript ID Bladder Breast Colon Lung Ovary Testis
ENST00000250018 0.190±0.00 0.444±0.00 2.511±0.00 0.193±0.00 0.527±0.00 0.441±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IE CIL_0001IE_0002 CGP 11:17788048-18042426
CIL_00041A CIL_00041A_0002 CGP 11:18017564-18106091

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004510 IEA tryptophan 5-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005829 TAS cytosol
GO:0007623 IEA circadian rhythm
GO:0008152 IEA metabolic process
GO:0009072 IEA aromatic amino acid family metabolic process
GO:0016597 IEA amino acid binding
GO:0016714 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0030279 IEA negative regulation of ossification
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0035902 IEA response to immobilization stress
GO:0042427 IEA serotonin biosynthetic process
GO:0043005 IEA neuron projection
GO:0044281 TAS small molecule metabolic process
GO:0045600 IEA positive regulation of fat cell differentiation
GO:0046219 TAS indolalkylamine biosynthetic process
GO:0046849 IEA bone remodeling
GO:0055114 IEA oxidation-reduction process
GO:0060749 IEA mammary gland alveolus development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000049298 Tph1-002 protein_coding Mus_musculus 0 1410
ENSMUST00000107669 Tph1-001 protein_coding Mus_musculus 0 1410
ENSMUST00000170251 Tph1-005 nonsense_mediated_decay Mus_musculus 0 785
ENSMUST00000172386 Tph1-006 nonsense_mediated_decay Mus_musculus 0 771
ENSMUST00000170045 Tph1-008 retained_intron Mus_musculus 0 405
ENSMUST00000168335 Tph1-003 protein_coding Mus_musculus 0 335
ENSMUST00000110264 Tph1-007 retained_intron Mus_musculus 0 322
ENSMUST00000163468 Tph1-004 retained_intron Mus_musculus 4e-23 115

Loading