C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000115835 Grin2a-001 ENSMUSG00000059003 10090 - 16:9577710-9994921 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainLiverOvaryPlacentaTestisENSMUST00000115835
Transcript ID Adrenal Bladder Brain Liver Ovary Placenta Testis
ENSMUST00000115835 0.036±0.02 0.020±0.00 0.905±0.80 0.003±0.00 0.017±0.00 0.005±0.00 0.031±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000EM CIL_0000EM_0002 CGP 16:8830100-9994921

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001964 IMP startle response
GO:0001975 IMP response to amphetamine
GO:0004972 IMP N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005261 IMP cation channel activity
GO:0005262 IMP calcium channel activity
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0006816 IMP calcium ion transport
GO:0007268 IMP synaptic transmission
GO:0007611 IMP learning or memory
GO:0007612 IMP learning
GO:0007613 IMP memory
GO:0007626 TAS locomotory behavior
GO:0008021 IDA synaptic vesicle
GO:0008104 IGI protein localization
GO:0008270 ISS zinc ion binding
GO:0008542 IMP visual learning
GO:0009611 IGI response to wounding
GO:0009986 IDA cell surface
GO:0014069 IDA postsynaptic density
GO:0016020 IDA membrane
GO:0017146 IPI N-methyl-D-aspartate selective glutamate receptor complex
GO:0019233 IMP sensory perception of pain
GO:0022008 IMP neurogenesis
GO:0030054 IEA cell junction
GO:0030431 IMP sleep
GO:0033058 IGI directional locomotion
GO:0034220 IBA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0040011 IMP locomotion
GO:0042177 IGI negative regulation of protein catabolic process
GO:0042391 IMP regulation of membrane potential
GO:0042417 IMP dopamine metabolic process
GO:0042428 IMP serotonin metabolic process
GO:0042493 IMP response to drug
GO:0042734 IDA presynaptic membrane
GO:0043005 IDA neuron projection
GO:0043065 IGI positive regulation of apoptotic process
GO:0043197 ISA dendritic spine
GO:0045202 IDA synapse
GO:0045211 IDA postsynaptic membrane
GO:0045471 IMP response to ethanol
GO:0048167 IMP regulation of synaptic plasticity
GO:0050804 IMP regulation of synaptic transmission
GO:0051930 IMP regulation of sensory perception of pain
GO:0060078 IMP regulation of postsynaptic membrane potential
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0070588 IMP calcium ion transmembrane transport
GO:0097481 IDA neuronal postsynaptic density
GO:0098655 IMP cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000047094 GRIN2B (2 of 2)-201 protein_coding Danio_rerio 0 616
ENSDART00000103882 grin2db-201 protein_coding Danio_rerio 0 497
ENSDART00000144062 grin2db-001 protein_coding Danio_rerio 0 497
ENSDART00000128837 grin2da-001 protein_coding Danio_rerio 0 381
ENSDART00000121651 grin2da-202 protein_coding Danio_rerio 2e-16 94
ENST00000330684 GRIN2A-002 protein_coding Homo_sapiens 0 5790
ENST00000396573 GRIN2A-001 protein_coding Homo_sapiens 0 5962
ENST00000396575 GRIN2A-201 protein_coding Homo_sapiens 0 5003
ENST00000461292 GRIN2A-004 processed_transcript Homo_sapiens 0 388
ENST00000463531 GRIN2A-003 processed_transcript Homo_sapiens 0 486
ENST00000535259 GRIN2A-202 protein_coding Homo_sapiens 0 4080
ENST00000562109 GRIN2A-006 protein_coding Homo_sapiens 0 4597
ENST00000566665 GRIN2A-005 retained_intron Homo_sapiens 0 828
ENST00000566670 GRIN2A-009 processed_transcript Homo_sapiens 0 542
ENST00000566683 GRIN2A-007 processed_transcript Homo_sapiens 0 246
ENST00000568247 GRIN2A-008 processed_transcript Homo_sapiens 0 647

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