C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: thymine DNA glycosylase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000151390 Tdg-002 ENSMUSG00000034674 10090 + 10:82629859-82650799 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000151390
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000151390 4.826±1.68 9.389±3.44 2.939±0.41 12.098±1.75 3.834±1.47 5.964±2.65 0.733±0.17 2.189±0.62 3.316±0.58 4.881±0.95 0.721±0.20 7.972±1.94 4.161±1.53 0.980±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000002 CIL_000002_0003 CGP 10:82619851-82650799
CIL_0002S6 CIL_0002S6_0002 CGP 10:82629828-82690650

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001104 IGI RNA polymerase II transcription cofactor activity
GO:0003690 ISS double-stranded DNA binding
GO:0005080 IPI protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005886 IEA plasma membrane
GO:0006284 IDA base-excision repair
GO:0006298 ISS mismatch repair
GO:0006366 IGI transcription from RNA polymerase II promoter
GO:0008134 IEA transcription factor binding
GO:0008263 IEA pyrimidine-specific mismatch base pair DNA N-glycosylase activity
GO:0009790 IMP embryo development
GO:0016568 IEA chromatin modification
GO:0016605 IDA PML body
GO:0019104 IDA DNA N-glycosylase activity
GO:0019904 IEA protein domain specific binding
GO:0030983 ISS mismatched DNA binding
GO:0032091 IDA negative regulation of protein binding
GO:0032183 IPI SUMO binding
GO:0035562 IDA negative regulation of chromatin binding
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0042803 ISS protein homodimerization activity
GO:0043566 IDA structure-specific DNA binding
GO:0080111 IMP DNA demethylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000266775 TDG-003 protein_coding Homo_sapiens 0 1085
ENST00000392872 TDG-001 protein_coding Homo_sapiens 0 1317
ENST00000537100 TDG-008 protein_coding Homo_sapiens 0 579
ENST00000540956 TDG-006 nonsense_mediated_decay Homo_sapiens 0 575
ENST00000542926 TDG-009 retained_intron Homo_sapiens 0 488
ENST00000543961 TDGP1-001 processed_pseudogene Homo_sapiens 0 968
ENST00000544861 TDG-004 protein_coding Homo_sapiens 0 1077

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